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dc.contributor.authorVillas Boas, Julia Dias
dc.date.accessioned2023-12-21T19:00:41Z-
dc.date.available2023-12-21T19:00:41Z-
dc.date.issued2017-04-28
dc.identifier.citationVILLAS BOAS, Julia Dias. Reatividade a diferentes tipos de estresse em equinos atletas. 2017. 104 f. Tese (Doutorado Multicêntrico de Pós-Graduação em Ciências Fisiológicas) - Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2017.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/10299-
dc.description.abstractO cavalo tem uma predisposição natural para o esporte, no entanto, o seu uso em competições pode resultar em problemas relacionados ao estresse que prejudicam seu desempenho esportivo e principalmente a sua saúde. Desta forma é fundamental não apenas entender como os diferentes fatores de risco e de resiliência a diferentes estressores influenciam a resposta ao estresse, como também desenvolver estratégias que possam prevenir ou minimizar os efeitos deletérios do estresse. Neste sentido a acupuntura é uma técnica milenar da Medicina Tradicional Chinesa que tem sido utilizada no tratamento e prevenções de doenças relacionadas ao estresse. O presente estudo propôs o uso de dois modelos de estresse: um físico (exercício físico) e outro psicológico (modelo de sobressalto) para verificar a reatividade ao estresse de cavalos atletas. Além disso, também foi avaliado se cavalos de diferentes modalidades esportivas apresentam respostas ao estresse de psicológico distintas e se acupuntura pode alterar as respostas ao estresse físico. No experimento 1, 16 equinos de corrida da raça Puro Sangue Inglês foram submetidos ao exercício a campo de alta intensidade e curta duração (12 m/s, 4min). Os intervalos RR para análise da Variabilidade da Frequencia Cardíaca foram adquiridos através do frequencímetro cardíaco Polar Equine™ e as amostras de sangue foram coletadas antes e, imediatamente, 2h, 4h, 6h, e 24h após o exercício. O exercício promoveu alterações autonômicas no balanço simpato-vagal uma vez que aumentou significativamente o componente de baixa frequência (LF), a frequência cardíaca e a razão LF/HF e diminuiu o componente de alta frequência (HF) (p < 0.01). Houve aumento do hematócrito, das proteínas plasmáticas, glicose e lactato plasmático imediatamente após o exercício (p < 0.001). Houve aumento (p<0.01) nos valores séricos de cortisol após 30 minutos, retornando aos valores basais após 60min. No entanto, não foi observado diferença significativa nas citocinas plasmáticas IL-1β e IL-6 entre os momentos após exercício e o momento basal. No experimento 2: os equinos do experimento 1 após o exercício foram aleatoriamente divididos em dois grupos: CTL (C2): Controle (sem manipulação) e ACUP (C2)ACUP (C2): animais submetidos a sessões semanais de acupuntura nos pontos VG1, C7, VG20 e B52 durante 10 semanas. Após o período de tratamento os animais repetiram o mesmo exercício e foram analisados os mesmos parâmetros. A acupuntura reduziu a razão LF/HF, promovendo uma recuperação mais rápida dos animais não apresentando influência nos demais parâmetros analisados. No experimento 3, foram utilizados 24 equinos, pertencentes a três modalidades equetres: Pólo (raça PSI) (n=9), Adestramento (raça Brasileiro de Hipismo) (n=6) e Enduro (Puro Sangue Árabe) (n=9) submetidos ao modelo experimental de sobressalto através da abertura abrupta de um guarda-chuva. Os resultados mostraram que cavalos de enduro apresentaram resposta autonômica induzida pelo sobressalto significativamente menos intensa que cavalos de Polo e Adestramento (menor razão LF/HF no momento do sobressalto), paradoxalmente cavalos de Enduro possuem níveis de cortisol em resposta ao sobressalto mais altos que cavalos de Polo. Não houve diferença entre as modalidades na resposta comportamental após o sobressalto, no entanto cavalos de Pólo apresentam níveis basais de cortisol significativamente mais altos que as demais modalidades e não variaram seus níveis de cortisol em resposta ao estresse. Dessa forma, podemos concluir que 1) o exercício a campo de alta intensidade e curta duração promoveu alterações adaptativas característica de estresse, podendo ser utilizado em estudos de reatividade ao estresse em cavalos de corrida; 2) a acupuntura tem um efeito modulador da resposta autonômica induzida pelo estresse em cavalos atletas e 3) as modalidades equestres de Adestramento, Polo e enduro apresentam reatividade ao estresse distintaspor
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopor
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectbem-estar animalpor
dc.subjectexercício físicopor
dc.subjectsobressaltopor
dc.subjectvariabilidade da freqüência cardíacapor
dc.subjectglicosepor
dc.subjectlactatopor
dc.subjectcortisolpor
dc.subjectcitocinas inflamatóriaseng
dc.subjectanimal welfareeng
dc.subjectphysical exerciseeng
dc.subjectstartlingeng
dc.subjectheart rate variabilityeng
dc.subjectglucoseeng
dc.subjectlactateeng
dc.subjectinflammatory cytokineseng
dc.titleReatividade a diferentes tipos de estresse em equinos atletaspor
dc.title.alternativeReactivity to different types of stress in equine athleteseng
dc.typeTesepor
dc.description.abstractOtherThe horse has a natural predisposition for the sport, however, its use in competitions can result in stress related problems that impair its sporting performance and especially its health. In this way it is fundamental not only to understand how the different risk and resilience factors to different stressors influence the response to stress, but also to develop strategies that can prevent or minimize the deleterious effects of stress. In this sense, acupuncture is an ancient technique of Traditional Chinese Medicine that has been used in the treatment and prevention of stress-related diseases. The present study proposed the use of two models of stress: one physical (physical exercise) and another psychological (startle model) to verify the reactivity to the stress of athletes horses. In addition, it was also evaluated if horses of different sporting modalities present different psychological stress responses and if acupuncture can alter the responses to physical stress. In the experiment 1, 16 Thoroughbred race horses were submitted to a exercise in the field of high intensity and short duration (12 m / s, 4 min). The RR intervals for analysis of the Heart Rate Variability were acquired through the Polar Equine ™ heart rate monitor and blood samples were collected before and immediately after 2h, 4h, 6h, and 24h after exercise. The exercise promoted autonomic alterations in the sympatho-vagal balance since it significantly increased the low frequency component (LF), the heart rate and the LF / HF ratio, and decreased the high frequency component (HF) (p <0.01). There was an increase in hematocrit, plasma proteins, glucose and plasma lactate immediately after exercise (p <0.001). There was an increase (p <0.01) in serum cortisol values after 30 minutes, returning to baseline values after 60 min. However, no significant difference was observed in plasma cytokines IL-1β and IL-6 between moments after exercise and baseline. In experiment 2, horses of the experimental group 1 after exercise were randomly divided into two groups: CTL (C2): Control (without manipulation) and ACUP (C2)): animals submitted to weekly sessions of acupuncture at points VG1, C7, VG20 and B52 for 10 weeks. After the treatment period the animals repeated the same exercise and the same parameters were analyzed. Acupuncture reduced the LF / HF ratio, promoting a faster recovery of the animals, showing no influence on the other parameters analyzed. In the experiment 3, 24 equines were used, from three equestrian modes: Polo (PSI) (n = 9), Dressage (Brazilian Horse Riding) (n = 6) and Endurance (n=6) were subjected to the experimental model of startling through the abrupt opening of an umbrella. The results showed that endurance horses presented a significantly less intense startle-induced autonomic response than Polo and Dressage horses (lower LF / HF ratio at the time of the jump), paradoxically Enduro horses have cortisol levels in response in response to the startle than Polo horses. However, there was no difference between the modalities in the behavioral response after the startle, and Polo horses had significantly higher baseline levels of cortisol than the other modalities and did not change their cortisol levels in response to stress. Thus, we can conclude that 1) the exercise in the field of high intensity and short duration promoted adaptive changes characteristic of stress, being able to be used in studies of reactivity to stress in race horses; 2) acupuncture has a modulating effect on the stress-induced autonomic response in athletic horses, and 3) the equestrian modalities of Dressage, Polo and Endurance present different stress reactivityeng
dc.contributor.advisor1Medeiros, Magda Alves de
dc.contributor.advisor1ID036.592.487-38por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/6392136073564306por
dc.contributor.referee1Godoi, Fernanda
dc.contributor.referee2Malvar, David do Carmo
dc.contributor.referee3Szabó, Márcia Valéria Rizzo Scognamillo
dc.contributor.referee4Costa, Maria Fernanda de Mello
dc.creator.Latteshttp://lattes.cnpq.br/5651495295929397por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Ciências Biológicas e da Saúdepor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicaspor
dc.relation.referencesACHARYA, R. U.; JOSEPH, P. K.; KANNATHAl, N.; LIM, C.M.; SURI, J.S. Heart rate variability: a review. Med Bio Eng Comput, v.44(12), p.1031-51, 2006. 2. ADAMS, A.; KATEPALL;, M. P. , KOHLER, K.; REEDY, S. E. ; STILZ, J. P. ; VICK, M. ; FITZGERALD, B. P. ; LAWRENCE, L. M. ; HOROHOV, D, W.. Effect of body condition, body weight and adiposity on inflammatory cytokine responses in old horses. Vet. Immunol. Immunopathol, v. 12, p. 286–294, 2009. 3. AGELINK, M.W.; SANNER, D.; EICH, H.; PACH, J.; BERTILING, R.; LEMMER, W.; KLIESER, E.; LEHMANN, E.. Does acupuncture influence the cardiac autonomic nervous system in patents with minor depression on onxiety disorders? Fortschr Neurol Psychitr, v.71, p. 141-149, 2003. 4. AIRES, M. M. Fisiologia. 2.ed. Rio de Janeiro: Guanabara Koogan, 1999.; p.830- 835, 1999. 5. AKIMOTO T, NAKAHORI C, AIZAWA K, KIMURA F, FUKUBAIASHI T, KONO I. Acupuncture and responses of immunologic and endocrine markers during competition. Medicine & Science in Sports & Exercise, v.35, n.8, p. 1296-302. 2003. 6. ALEXANDER, S.L., IRVINE, C.H.G., ELLIS, M.J., DONALD, R.A. The effect of acute exercise on the secretionof corticotropin-releasing factor, arginine vasopressin, and adrenocorticotropin as measured in pituitary venous blood from the horse. Endocrinology, v. 128, p. 65–72. 1991. 7. ANDERSON, B. A.; NIELSEN, D.; MCKEE, A.. Jeffres, and B. Kligler, “Acupuncture and heart rate variability: a systems level approach to understanding mechanism,” Explore, v. 8, no. 2, p. 99–106, 2012. 8. ANDREWS, F. M.; GEISER, D.R.; WHITE, S.L.; WILLIAMSON, L.H.; MAYKUTH P.L.; GREEN, E.M. Haematological and biochemical changes in horses competing in a 3 star horse trial and 3-day-event. Equine Veterinary Journal, v. 20, p. 57-63, 1995. 9. ANGELI A.L.; LUNA S. P. L. Aquapuncture improves metabolic capacity in Thoroughbred horses. J Equine Vet Sci 2008, 28:525–31, 2008. 10. ANGELI, A.L.; LUNA, S.P.L.; GAROTTI, J.R.. Aquapuntura no tratamento das síndromes equinas: há efeito sobre os valores hematológicos e de cortisol? Ars veterinaria,Jaboticabal, SP, v.24, n.3, p. 153-160. 2008. 11. AUBERT, A.E.; Seps, B.; Beckers, F. Heart rate variability in athletes. Sports Med. v. 33(12), p.889-919, 2003. 12. BARLAS P.; ROBIN SON J.; ALLEN J.; BAXTER GD. Lack of effect of acup un ct ure upon sign s an d sym ptom s of delayed on set m uscle soreness. Clin Physiol,20:449–56, 2000. 13. BARLY, W.; GEOR, R. J.; HINCHCLIFF, K. W.; KANEPS, A. J. Equine Sport Medicine and Surgery - Basic and clinical sciences of the equine athlete. Philadelphia: Saunders Company, 2004. p. 7, 55, 56 e 771, 2004. 14. BASELLI G.; CERUTTI S.; CIVARDI S.; LOMBARDI F.; MALLIANI A.; MERRI M.; RIZZO G. Heart rate variability signal processing: a quantitative approach 87 as an aid to diagnosis in cardiovascular pathologies. Int J Biomedi Comp 20: 51-70, 1987. 15. BAUDRIE, V.; TULEN, J.H.; BLANC, J.; ELGHOZI, J.L.. Autonomic components of thecardiovascular responses to an acoustic startle stimulus in rats. J. Auton.Pharmacol. v. 17, p. 303–309, 1997. 16. BAY-RICHTER, C.; BAY-RICHTER, S.; JANELIDZE, L.; HALLBERG, L. Changes in behaviour and cytokine expression upon a peripheral immune challenge, Behav. Brain Res.222 (2011) 193–199, 2011. 17. BELMIRO, H.; OLIVEIRA, D. V.; CAMILOTTI, C.M.. Efeitos da acupuntura no desempenho motor de atletas. Conexões. v. 11, n. 3, 2013. 18. BERNARD, L. C., KRUPAT, E.. Health Psychology: Biopsychosocial Factors in Health and Illness. New York: Harcourt Brace College Publishers. 1994. 19. BING, Z.; BING, F.; CESSELIN, S.; BOURGOIN, A. M.; CLOT, M. AND LE BARS, D. “Acupuncture-like stimulation induces a heterosegmental release ofMet-enkephalin-like material in the rat spinal cord,” Pain, vol. 47, no. 1, pp. 71–77, 1991. 20. BIRCH, S. et al. What have reviews of the effi cacy and safety of acupunture told us so far? Journal of Alternative Complementary Med. v. 10, n. 3, p. 468- 480, 2004 21. BLECHA, F. Immune system response to stress. CABI Publishing, p.111-122. 2000. 22. BORELL, E.V; LANGBEIN, J; DESPRÉS, G; HANSEN, S; LETERRIER, C; MARCHANT-FORDE, J; MARCHANT-FORDE,R; MINERO, M; MOHR, E; PRUNIER, A; VALANCE, D; VEISSIER, I.. Heart rate variability as a measure of autonomic regulation of cardiac activity for assessing stress and welfare in farm animals. Physiology & Behavior, v. 92, p.293–316. 2007. 23. BOSCH, E. V. D.; GURAY, J. Y. Acupuncture points and meridians in the horse. 2nd ed. Germany: Sonntag, 1999. 24. BRADLEY, M. M.; BRADLEY, B. N. AND LANG, P. J. “Startle reflex modification: emotion or attention?” Psychophysiology, v. 27, no. 5, p. 513– 522, 1990. 25. BRIETZKE, E.; BRIETZKE, M.; SCHEINBERG, B. Therapeutic potential of interleukin-6antagonism in bipolar disorder. Med. Hypotheses, v. 76, p. 21– 23, 2011. 26. BUONORA, G.S.; AFONSO, J.A.B.; ALMEIDA, H.B.; SILVEIRA ALVES, G.E. Estudo da ocorrência de lesões gástricas em cavalos de vaquejada. Brasilian Journal of Veterinary Research and Animal Science, São Paulo, v.41, suplementoo, p.263-264, 2004. 27. CAIN, M. J. Acupuncture diagnosis and treatment of the equine: a five element tutorial. Kentuky: M.J.Cain Books, 2003. 28. CALABRESE, E.J.. Converging concepts: adaptive response, preconditioning, and the Yerkes–Dodson Law are manifestations of hormesis. Ageing Research Reviews: v. 7: p. 8-20. 2008; 29. CAMPBELl, E. H.. Lactate-driven equine conditioning programmes. The Veterinary Journal, v. 190(2), p. 199-207, 2011. 88 30. CAPUTO, F.; OLIVEIRA, M. F. M.; GRECO, C. C.; DENADAI, B. S. Exercício aeróbio: Aspectos bioenergéticos, ajustes fisiológicos, fadiga e índices de desempenho. Revista Brasileira de Cineantropometria e Desempenho Humano, Florianópolis, v. 11, n. 1, p. 94-102, 2009. 31. CASTIGLIONI, P.; DI RIENZO, M.; RADAELLI, A.. Effects of autonomic ganglionblockade on fractal and spectral components of blood pressure and heart ratevariability in free-moving rats. Auton. Neurosci 27. 2013. 32. CAYADO, P.: MUNOZ-ESCASSI, B.; DOMiNGUEZ, c.; MANLEY, W.; OLABARRl, B.; SANCHEZ DE LA MUELAS, M.; CASTEJON, f.; MARANON, G.; VARA, E.. Hormone response to training and competition in athletic horses. Equine vet. J. SuppI. v. 36, p. 274-278. 2006. 33. CHEN, J.; HUANG, C.; XIAO, D.; CHEN, H.P.; CHENG, J.S. Expression of interleukin-6 mRNA in ischemic rat brain after electroacupuncture stmulation. Acupunct Electrother Res.: 28(3-4): 157-66, 2003. 34. CHRISTENSEN, J.W.; ZHARKIKH, T.; CHOVAUX, E.. Object recognition and generalisation during habituation in horses. Applied Animal Behaviour Science, v. 129, p. 83–91. 2010. 35. CHROUSOS, G.P.; LORIAUX, D.L.; GOLD, P.W. Mechanisms of physical and emotional stress. Adv Exp Med Bio, v.245, p. 3-11. 1988. 36. CHUNG J. W. Y.; CHUNG, V. C. M.; YAN, A.; ZHANG H. “Effect of acupuncture on heart rate variability: a systematic review,” Evidence- Based Complementary and Alternative Medicine, vol. 2014, p. 19 , 2014. 37. COELHO, C. S.; GAMA, J. A. N.; LOPES, P. F. R.; SOUZA, V. R. C. Glicemia e concentrações séricas de insulina, triglicérides e cortisol em equinos da raça Mangalarga Marchador após exercício físico. Pesq. Vet. Bras. v. 31, n. 9, p. 756-760, 2011. 38. COOK, E.W. 3rd; HAWK, L.W. JR.; DAVIS, TL and STEVENSON, V.E.. Affective individual differences and startle reflex modulation. J Abnorm Psyshol, v. 100 (1), p. 5-13, 1991. 39. COGGAN, A.R. Plasma glucose metabolism during exercise in humans. Sports Medicine, v. 11, n. 2, p. 102-124, 1991. 40. COLAHAN, P. T.; KOLLIAS-BAKERT, C; LEUTENEGGER, C. M.; JONES, J. H.. Does training affect mRNA transciption for cytokine production in circulating leucocytes? Equine Vet. J. Suppl. 34, p.154–158, 2002. 41. COOMBES, J.S. Exercise-induced muscle damage, plasma cytokines, and markers of neutrophil activation. Med. Sci. Sports Exerc. 37, 737-745. 2005. 42. COVALESKY, M. E.; RUSSONIELLO, C. R.; MALINOWSKY, K. Effects of show-jumping performance stress on plasma cortisol and lactate concentrations and heart rate and behavior in horses. Journal of Equine Veterinary Science, v.12, n.4, p.315-327, 1995. 43. DARELLA, M.L. A atividade mental segundo o modelo da Medicina Tradicional Chinesa. Dissertação. Programa de Pós-Graduação em Engenharia de Produção – Centro Tecnológico. Universidade Federal de Santa Catarina, Florianópolis. 2001. 44. DESMECHT, D.; LINDEN, A.; AMORY, H.; ART, T.; LEKEUX, P. Relationship of plasma lactate production to cortisol release following completion of 89 different types of sporting events in horses. Veterinary Research Communications, v.20, n.4, p.371-379, 1996. 45. DEVRIES, A.C.K.S, CRAFT, T.K.S, GLASPER, E.R, NEIGH, G.N, ALEXANDER, J.K.. Social influences on stress responses and health. J. Psyneuen, v.32, p. 587-607. 2007. 46. DICKSON, W.M. Endocrinologia, reprodução e lactação. Glândulas endócrinas. In: SWENSON, M.J. Dukes:Fisiologia dos animais domésticos. Rio de Janeiro: Guanabara Koogan, p. 571-602. 1996. 47. DOBROMYLSKYJ, P., P. A. FLECKNELL, B. D. LASCELLES, H. LIVINGSTON, P. TAYLOR, AND A. WATERMAN-PEARSON. Pain assessment. In: Flecknell, P.A. (eds), Pain Manag An, p. 53–79. W.B. Saunders, London, UK. 2000. 48. DONOVAN, D.C.; JACKSON, C.A.; COLAHAN, P.T.; NORTON, N.; HURLEY, D.J. Exercise-induced alterations in pro-inflammatory cytokines and prostaglandin F2 alpha in horses. Vet Immunol Immunopathol, v. 118, p. 263- 269, 2007. 49. DRAEHMPAEHL, D.; ZOHMANN, A. Acupuntura no cão e no gato – Princípios básicos e prática científica. São Paulo: Roca, p.245. 1997. 50. EHRLICH, D.; HABER, P.. Influence of acupuncture on physical performance capacity and haemodynamic parameters. Int. Sports Med, v.13, p.486-491. 1992. 51. ERBER, R.; WULF, M.; AURICH, J.; ROSE-MEIERHÖFER, S.; HOFFMANN, G.; VON LEWINSKI, M.; MÖSTL E.; AURICH C. Stress response of three-year-old horse mares to changes in husbandry system during initial equestrian training. J. Equine Vet, Sci. ,33:1088–1094, 2013. 52. ERBER, R.; WULF, M.; AURICH, J.; ROSE-MEIERHÖFER, S.; HOFFMANN, G.; VON LEWINSKI, M.; MÖSTL E.; AURICH C. Stress response of three-year-old horse mares to changes in husbandry system during initial equestrian training. J. Equine Vet. Sci. 2013,33:1p. 088–1094, 2013. 53. ESHKEVARI, L.; ESHKEVARI, E.; PERMAUL, L. AND MULRONEY, S. E. “Acupuncture blocks cold stress-induced increases in the hypothalamuspituitary- adrenal axis in the rat,” Journal of Endocrinology, vol. 217, no. 1, p. 95–104, 2013. 54. ESHKEVARI, L.; ESHKEVARI, R.; EGAN, D.; PHILLIPS ET A.L. “Acupuncture at ST36 prevents chronic stress-induced increases in neuropeptide Y in rat,” Experimental Biology and Medicine, vol. 237, no. 1, p. 18– 23, 2012. 55. ESHKEVARI, L.; ESHKEVARI, R.; EGAN, D.; PHILLIPS, ET A.L. “Acupuncture at ST36 prevents chronic stress-induced increases in neuropeptide Y in rat,” Experimental Biology and Medicine, vol. 237, no. 1, p. 18– 23, 2012. 56. EVANS, D. L.; HARRIS, R. C.; SNOW, D. H. Correlation of Racing Performance with Blood Lactate and Heart Rate After Exercise in Thoroughbred Horses. Equine Veterinary Journal, v. 25, n. 5, p. 441- 445, 1993. 57. FERLAZZO, A.; MEDICA, P.; CRAVANA, C.; FAZIO, E. Endocrine changes after experimental showjumping. Comp Exerc Phys. 6:59–66. 2009. 58. FERRAZ, G. C. Respostas endócrinas, metabólicas, cardíacas e hematológicas de eqüinos submetidos ao exercício intenso e à 90 administração de cafeína, aminofilina eclembuterol. 2006. Tese (doutorado) - Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, 2006. 59. FERRAZ, G. C.; D’ANGELI , F. H. F.; TEIXEIRA-NETO, A. R.; FREITAS, E. V. V.; LACERDA-NETO, J. C.; QUEIROZ-NETO, A. Blood lactate threshold reflects glucose responses in horses submitted to incremental exercise test. Arq. Bras. Med. Vet. Zootec.; v.60, n.1, p.256-259, 2008. 60. FERRAZ, G. C.; TEIXEIRA-NETO, A. R.; PEREIRA, M. C.; LINARDI, R. L.; LACERDANETO, J. C.; QUEIROZ-NETO, A. Influência do treinamento aeróbio sobre o cortisol e glicose plasmáticos em equinos. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, v.62, n.1, p.23- 29, 2010. 61. FERRAZ, G.C.; ESCODRO, P.B.; QUEIROZ NETO, A. Fisiologia do exercício equino: ferramenta para o desempenho atlético de cavalos atletas. Braz. J. Equine Med., v.12, p.6-8, 2007. 62. FLEMING, P. Diagnostic acupuncture palpation examination in the horse. In: SHOEN, A. M. (Ed). Veterinary acupuncture: ancient art to moderm medicine. St, Louis: Mosby, p. 433-41, 2001 63. FOWLER, V.L.; KENNEDY, M.; MARLIN, D. A comparison of the Monty Roberts training technique with a conventional UK technique for the initial training of riding horses. Anthrozoos. v. 225, p. 302–321, 2012. 64. FRANCI, C.R.. Estresse:Processos adaptativos e não adaptativos. In: ANTUNES-Rodrigues, F., et al. Neuroendocrinologia Básica Aplicada. 1 ed. Rio de Janeiro: Guanabara Koogan, p.200-223. 2005. 65. FRIEMEL, C.M.; ZIMMER, A. and SCHNEIDER, M. "The CB1 receptor as an important mediador of hedonic reward processing", Neuropsycopharmacology, v. 79, p. 83-89, 2014. 66. FREESTONE, J. F.; WOLFSHEIMER, K. J.; KAMERLING, S. G.; CHURCH, G.; HAMRA, J.; BAGWELL, C. Exercise induced hormonal and metabolic changes in Thoroughbred horses: effects of conditioning and acepromazine. Equine Veterinary Journal, v.23, n.3, p.219-223, 1991. 67. FRY, L.D.M.; NEARY N.S.S.M.; ROCK J.S.; RYCHEL. J.K. Acupuncture for Analgesia in Veterinary Medicine. Topics in Companion Animal Medicine - V. 29, Issue 2, p. 35–42, 2014. 68. GODOI, T. L. O; VILLAS-BOAS, J. D.; ALMEIDA, N. A. D. S.; TRIGO, P. I.; ALMEIDA, F. Q. DE; MEDEIRO , M. A. DE “Pharmacopuncture versus acepromazine in stress responses of horses during road transport,” Journal of EquineVeterinary Science, vol. 34, no. 2, pp. 294–301, 2014. 69. GOMIDE, L. M. W.; MARINS, C. B.; OROZCO, C. A. G. et al. Blood lactate concentrations of horses competing in the resistance phase of 3-day combined training event. Ciência Rural, v.36, n.2, p.509-513, 2006. 70. GORDON, M.E.; MCKEEVER, K.H.; BETROS, C.L.; MANSO FILHO, H.C. Exercise-induced alterations in plasma concentrations of ghrelin, adiponectin, leptin, glucose, insulin and cortisol in horses. Vet. Journal. v. 173, p. 532-540, 2007. 91 71. GORECKA, A.; BAKUNIAK, M. H.; CHRUSZCZEWSKI T.; JEZIERSKI, T. A. “A note on the habituation to novelty in horses: handler effect,” Animal Science Papers and Reports, vol. 25, no. 3, pp. 143–152, 2007. 72. GRAAF-ROELFSEMA, E.; KEIZER, H.A.; BREDA E.V. et al. Hormonal responses to acute exercise, training and overtraining: A review with emphasis on the horse. Vet. Q., v.29, p.82-101, 2007. 73. GRAHAM, F.K.. Distinguishing among orienting defense and startle reflexes.In: Kimmel, H.D., Van Olst, E.H., Orlebeke, J.F. (Eds.), The Orienting Reflex inHumans. Erlbaum, New Jersey. 1979. 74. GUIMARÃES, C.M.,PINGE, M.C.M., YAMAMURA, Y., MELLO L.E.A.M.. Effects of acupuncture on behavioral, cardiovascular and hormonal responses in restraint-stressed Wistar rats. Braz J Med Biol Res, v.30, n.12, p.1445-50. 1997. 75. HADA, T.; ONAKA, T.; TAKAHASHI, T.; HIRAGA, A.; YAGI, K. Effects of novelty stress on neuroendocrine activities and running performance in thoroughbred horses. J Neuroendocrinol v.15, p. 638-648, 2003. 76. Hall, B. M.. T Cells: Soldiers and Spies-The Surveillance and Control of Effector T Cells by Regulatory T Cells. Clin J Am Soc Nephrol, 2015. 77. HAN, S.H.; YOON, Y.W.; CHO, C.-J.; KIM, T.; MIN, B.I. “Inhibitory effects of electroacupuncture on stress responses evoked by tooth-pulp stimulation in rats,” Physiology and Behavior, v. 66, no. 2, p. 217–222, 1999. 78. HARMAN, J. C. Backs, performance and acupuncture. In: Annual convention of the American association of equine practitioners, v. 39, p. 337-348. 1993. 79. HEIRD, J.C.; WHITAKER, D.D.; BELL, R.W.; RAMSEY, C.B.; LOKEY, C.E.. The effects ofhandling at different ages on the subsequent learning ability of 2- year-oldhorses. Appl. Anim. Behav. Sci., v. 15, p. 15–25, 1986. 80. HINES, M.T.; SCHOTT II, H.C.; BAYLY, W.M.; LEROUX, A.J. Changes in limphocytes subpopulation following prolonged exercise in horse. In: Annual Veterinary Medical Forum, v. 12, p. 1016, 1994. 81. HODGSON, D. R.; ROSE, R. J. Effects of a nine-month endurance training programme on muscle composition in the horse. Veterinary Record, v.121, p. 271-274, 1987. 82. HODGSON, D. R.; ROSE, R. J. The athletic horse: Principles and practice of equine sports medicine. 1ª ed. Philadelphia: W. B. Saunders Company, p. 245- 258, 1994. 83. HOLLAND, J.L.; KRONFELD, D.S.; MEACHAM, T.N.. Behavior of horses is affected bysoy lecithin and corn oil in the diet. J. Anim. Sci. v. 74, p. 1252– 1255, 1996. 84. HOSHI, R. A. Variabilidade da freqüência cardíaca como ferramenta de análise da função autonômica: revisão de literatura e comparação do comportamento autonômico e metabólico em recuperação pós-exercício. Dissertação. Unesp. 2009. 85. HOWREN, M.B.; HOWREN, D.M.; LAMKIN, J. Associations of depression with C-reactiveprotein, IL-1, and IL-6: a meta-analysis. Psychosom. Med. v. 71, p. 171–186, 2009. 92 86. HWANG, D.S.; HWANG, H.; KIM, K.; SEO, J. C.; SHIN, I. H.; KIM, D. H.; AND KIM Y.S. “Sympathomodulatory effects of Saam acupuncture on heart rate variability in night-shift-working nurses” Complementary Therapies in Medicine, v. 19, supplement 1, p. S33– S40, 2011. 87. HWANG, Y. C., EGERBACHER, M. Anatomy and classification of acupoints. In:______. SCHOEN, A. M. (Ed.). Veterinary acupuncture: ancient art to modern medicine. St. Louis: Mosby, 2001. p. 19-25. 88. HYPPÄ, S.; PÖSÖ, A. R. Fluid eletrolyte, and acid-base responses to exercise in racehorses. Veterinary Clinics of North America: Equine Practice, v. 14, n. 1, p. 121-135, 1998 89. IMAI, K.; IMAI, H.; ARIGA, C.; CHEN, C.; MANTYH, T. N.; TAKAHASHI T. “Effects of electroacupuncture on gastric motility and heart rate variability in conscious rats”, Autonomic Neuroscience: Basic and Clinical, v. 138, no. 1-2, p. 91–98, 2008. 90. IMURA, H.; FUKATA J. I.; Mori, T.. Cytokines and endocrine fun ction: an interaction between the immune and neuroendocrine systems. Clin. Endocrinol., v. 35: p. 107-115, 1991. 91. JABLONSKA, E.M. et al. Changes is some haematological and matabolic indices in young horses during the first years of jump-training. Equine Veterinary Journal, v.23, n.4, p.309-311. 1991. 92. JANCZAREK, I.; KĘDZIER KI, W.; TACHUR KA, A.; WILK, I.; KOL TRUNG, R.; STRZELEC, K. Autonomic nervous system activity in purebred Arabian horses evaluated according to the low frequency and high frequency spectrum versus racing performance. ACTA VET. BRNO, v. 85, p. 355-362, 2016. 93. JANCZAREK, I.; TACHUR KA, A.; KĘDZIER KI, W.; WILK, I. Responses of horses of various breeds to a sympathetic training method. J. Equine Vet. Sci. 2013,33:794–801, 2013. 94. JANG, M.H., SHIN, M.C., LEE, T.H., LIM, B.V., SHIN, M.S., MIN, B.I., CHO, S., KIM, E.H., KIM, C. J. Acupunture supresses ischemia-induced increase in c- Fos expression and apoptosis in the hippocampal CA1 region gerbils. Neurosci. Lett. v. 347, p. 5-8. 2003. 95. JEUNE, S. S. L.; CRYSTAL, A.; WILLIAM, S.; BRUN, O.H.; PYPEN, D.; HAJIM, E.; JAM, E.H. Does Acupuncture Acutely Affect Heart Rate Variability in Horses? Journal of Equine Veterinary Science - v. 34, Issue 9, p.1084–1090, 2014. 96. KARVELAS, B.R.; HOFFM, A.N.; ZENI, A.I. Acute effects of acupu ncture on physiological and psychological responses to cycle ergometry. Arch Phys Med Rehabil, v. 77, p. 1256–9, 1996. 97. KATO, T.; OHMURA, H.; HIRAGA, A.; WADA, S.; KUWAHARA, M.; TSUBONE, H. Changes in heart rate variability in horses during immersion in warm springwater. American J Vet Res, v. 64, p. 1482-1485, 2003. 98. KEELING, L., P. JENSEN, P.. Behavioral disturbances, stress and welfare. In: Jensen, P. (eds), The Ethology of Domestic Animals: An Introductory Text. CABT Publishing, p. 79–98. 2002. 93 99. KEELING, L.J., JONARE, L., LANNEBORN, L.. Investigating horsehumaninteractions: the effect of a nervous human. Vet. J, v. 181, p. 70–71. 2009. 100. KIM Y.S. et al. The practice of Korean medicine: an overview of clinical trials in acupuncture. Evidence-Based Complementary and Alternative Medicine, v.2, n.3, p.325- 352, 2005. 101. KIM, H.; KIM, H.J.; PARK, S.M.; HAN, A.L. “The effects of acupuncture stimulation at PC6 (Neiguan) on chronic mild stress-induced biochemical and behavioral responses,” Neuroscience Letters, vol. 460, no. 1, pp. 56–60, 2009. 102. KIM, Y.K.; KIM, K.S.; NA, A.M.; MYINT, B.E.. The role of proinflammatorycytokines in neuroinflammation, neurogenesis and the neuroendocrinesystem in major depression, Prog. Neuropsychopharmacol. Biol. Psychiatry(2015), http://dx.doi.org/10.1016/j.pnpbp.2015.06.008, 2015. 103. KINGSTON, J.K. Hematologic and serum biochemical responses to exercise and training. IN: HINCHCLIFF, K.W.; KANEPS, A.J.; GEOR, R. J. Equine Sports Medicine and Surgery: Basic and Clinical Sciences of the Equine Athlete, Philadelphia: W.B.Saunders. p.940-948, 2004 104. KNARDAHL, S.; ELAM, M.; OLAUSSON, B.; WALLIN, B.G. Sympathetic nerve activity after acupuncture in humans. Pain, v. 75, p. 19–25, 1998. 105. Koch, K.; A. Schmid, and H.-U. Schnitzler, “Pleasure attenuation of startle is disrupted by lesions of the nucleus accumbens,” NeuroReport, v. 7, no. 8, p. 1442–1446, 1996. 106. KOCH, M. “The neurobiology of startle,” Progress in Neurobiology, v. 59, no. 2, p. 107–128, 1999. 107. KWON, S.; KWON, B.; LEE, M.; YEOM, B.J.; SUR, M.; KIM, S.T.; KIM, H.J.; PARK, H.; LEE, D.H. Modulatory effects of acupuncture on murine depression-like behaviorfollowing chronic systemic inflammation. Brain Res. v. 1472, p. 149–160, 2012. 108. LACOMBE, V.A.; HINCHCLIFF, K.W.; TAYLOR, L.E. Interactions of substrate availability, exercise performance, and nutrition with muscle glycogen metabolism in horses. Journal of the American Veterinary Medical Association, v. 223, n.11, p. 1576-1585, 2003 109. LANDERS, T.A. Professional Care of the Racehorse: A Guide to Grooming, Feeding, and Handling the Equine Athlete. Eclipse Press, Lexington, KY Low PA 1993: Autonomic nervous system function. J Clin Neurophysiol 10: 14-27, 2006.. 110. LANG, P. J.; LANG, M. M.; BRADLEY, A.; CUTHBERT, B. N. “Emotion, attention, and the startle reflex,” Psychological Review, v. 97, no. 3, p. 377– 395, 1990. 111. LANSADE, L.; LANSADE, C.; NEVEUX, A.; LEVY, F. “A few days of social separation affects yearling horses’ response to emotional reactivity tests and enhances learning performance,” Behavioural Processes, v. 91, no. 1, p. 94–102, 2012. 94 112. LANSADE, M.F.; BOUISSOU, A.; ERHARD, H. W. “Fearfulness in horses: a temperament trait stable across time and situations,” Applied Animal Behaviour Science, v. 115, no. 3-4, p. 182–200, 2008. 113. LE JEUNE, S. S.; LE JEUNE, C.; WILLIAMS, A.; PYPENDOP, B.H.; OHMURA, H.; JONES, J. H. “Does acupuncture acutely affect heart rate variability in horses?” Journal of Equine Veterinary Science, v. 34, no. 9, p. 1084–1090, 2014. 114. LEE, H.J.; LEE, B.; LEE, S.H.; CHOI, E.A. “Electroacupuncture reduces stress-induced expression of c-Fos in the brain of the rat,” American Journal of Chinese Medicine, v. 32, no. 5, p. 795– 806, 2004. 115. LEE, S.; LEE, M. S.; LEE, J.Y.; CHOI, S.W.; LEE, S.Y.; JEONG, A.; ERNST, E. “Acupuncture and heart rate variability: a systematic review,” Autonomic Neuroscience: Basic and Clinical, v. 155, no. 1-2, p. 5–13, 2010. 116. LEKEUX, P.; ART, T.; LINDEN, A.; DESMECHT, D.; AMORY, H. Heart rate, hematological and serum biochemical responses to show jumping. Equine exercise physiology 3, p. 385-390, 1991. 117. LEWINSKI et al.. Cortisol release, heart rate and heart rate variability in the horse and its rider: Different responses to training and performance. The Veterinary Journal, v. 197, Issue 2, p. 229-232, 2013. 118. LI, Q.Q.; Li, G.X.; SHI, Q.; XU, J.; WANG, C.Z.; LIU, A.; WANG, L.P. “Acupuncture effect and central autonomic regulation,” Evidence- Based Complementary and Alternative Medicine, v. 2013, p. 6, 2013. 119. LIAO, Y.Y.; LIAO, K.; SETO, H.; SAITO, M.; FUJITA, A.; KAWAKAMI, M. “Effects of acupuncture on adrenocortical hormone production. (II) Effect of acupuncture on the response of adrenocortical hormone production to stress,” American Journal of Chinese Medicine, vol. 8, no. 1-2, pp. 160–166, 1980. 120. LIBURT, N.R.; ADAMS, A.A.; BETANCOURT, A.; HOROHOV, D.W.; MCKEEVER, K.H. Exercise-induced increases in inflammatory cytokines in muscle and blood of horses. Equine Vet. J., v. 42, p. 280-288, 2010. 121. LIMEHOUSE,J.B.; TAYLOR-LIMEHOUSE,P.A.. Conceitos Orientais da Acupuntura. In: SHOEN,A. M.. Acupuntura Veterinária. 2 ed. São Paulo:ROCA, cap.6, p.76-90. 2006. 122. LIN, J.H. et al. Sustainable veterinary medicine for the new era. Revue scientifique et technique (International Office of Epizootics), v. 22, n. 3, p. 949- 964, 2003. 123. LINDEN, A.; ART, T.; AMORY, H.; DESMECHT, D.; LEKEUX, P. Effect of 5 different types of exercise, transportation and ACTH administration of plasma cortisol concentration in sport horses. Equine Exerc Physiol., v.3, p. 391–396, 1991. 124. LINDINER, M. I. Acid-base physiology during exercise and in response to training. In: HINCHCLIFF, K. W.; KANEPS, A. J.; GEOR, R. J. Equine Sports Medicine and Surgery. Philadelphia: Saunders, p. 872-897, 2004. 125. LINDNER, A. Use of blood biochemistry for positive performance diagnosis of port horses in practice. Revue de Médecine Vétérinaire, v. 151, p. 611-618, 2000. 95 126. LIU, Q.; LIU, B.; LI, H.Y.; ZHU, Y.Q.; WANG, J.; YU, G.C. Glia atrophy in thehippocampus of chronic unpredictable stress-induced depression model ratsis reversed by electroacupuncture treatment. J. Affect. Disord. v. 128, p. 309–313, 2011. 127. LOFTUS, L.; MARKS, K.; JONES-MCVEY, R.; GONZALES, J.L.; FOWLER, V.L. *Monty Roberts’ Public Demonstrations: Preliminary Report on the Heart Rate and Heart Rate Variability of Horses Undergoing Training during Live Audience Events. Animals (Basel). 2016 Sep, 6(9): 55, 2016 Sep. 128. LU, J.; SHAOA, R.H.; HU, L.; TU, Y.; GUO, J.Y. Potential antiinflammatory effects of acupuncture in a chronic stress model of depression in rats. Neuroscience Letters, v. 618,p. 31–38, 2016. 129. LUNA, S. P. L.; TAYLOR, P. M. 1998. Effect of eletroacupuncture on endogenous opioids, AVP, ACTH, cortisol and catecholamine concentrations measures in the cerebroespinal fluid (CSF), peripheral and pituitary effluente plasma of ponies. In: ANNUAL INTERNATIONAL CONGRESS ON VETERINARY ACUPUNCTURE, 24., 1998, Taiwan. Proceedings. Taiwan, I.V.A.S., p. 172-174, 1998. 130. LUNA, S. P. L.; LUNA, A. L.; ANGELI, C. L.; FERREIRA, V.; LETTRY, A.; SCOGNAMILLO-SZAB´O, M. “Comparison of pharmacopuncture, aquapuncture and acepromazine for sedation of horses,” Evidence- Based Complementary and Alternative Medicine, vol. 5, no. 3, pp. 267–272, 2008. 131. LUNA, S.P.L. Equine opioid, endocrine and metabolic responses to anaesthesia, exercise, transport and acupuncture. CambridgeTese (PhD) – Universidade de Cambridge. 1993. 132. LUNA, S.P.L.; ANGELI, A..L.; FERREIRA, C.L.; LETTRY, V.; SCOGNAMILLO-SZABO´, M. Comparison of Pharmacopuncture, Aquapuncture and Acepromazine for Sedation of Horses. eCAM, v. 5, n.3, p. 267–272. 2008. 133. MACIOCIA,G. Fundamentos da medicina chinesa. São Paulo: ROCA, p. 658. 2007. 134. MACQUEEN, G.; MACQUEEN, T. The hippocampus in major depression: evidence forthe convergence of the bench and bedside in psychiatric research, Mol.Psychiatry, v. 16, p. 252–264, 2011. 135. MAL, M.E., FRIEND, T.H., LAY, D.C., VOGELSANG, S.G., JENKINS, O.C.. Physiological responses of mares toshort-term confinement and isolation. J. Equine Vet.Sci, v. 11, p. 96–102, 1991. 136. MALINOWSKI, K.; SHOCK, E.J.; ROCHELLE, P.; KEARNS, C.F.; GUIRNALDA, P.D.; MCKEEVER, K.H. Plasma beta-endorphin, cortisol and immune responses to acute exercise are altered by age and exercise training in horses. Equine Vet J (Suppl), v. 36, p. 267–273, 2006. 137. MALLIANI, A.; PAGANI, M.; LOMBARDI, F.; CERUTTI, S.. Cardiovascular neuralregulation explored in the frequency domain. Circulation. v. 84, p. 482–492, 1991. 138. MALM, C. Exercise immunology: a skeletal muscle perspective. Exerc. Immunol. Rev. 8, p. 16-167, 2002. 96 139. MANM, F.. Acupuntura: a antiga arte chinesa de curar, São Paulo: Hermus, p.208. 1971. 140. MARC, M.; PARVIZI, N.; ELLENDORFF, F.; KALLWEIT, E.; ELSAESSER, F. Plasma cortisol and ACTH concentrations in the warmblood horse in response to a standardized treadmill exercise test and physiological markers for evaluation of training status. Journal of Animal Science, v.78, n.7, p.1936-1946, 2000. 141. MARLIN, D., NANKERVIS, K. Equine Exercise Physiology. Blackwell Science, 296p. 2002. ROSE, R. J., PURDUE, R. A., HENSLEY, W. Plasma biochemistry alterations in horses during an Endurance ride. Equine Veterinary Journal. v. 9, p. 122–126, 1977. 142. MARQUES, M. S. Influência do exercício físico sobre os níveis de lactato plasmático e cortisol sérico em cavalos de corrida. São Paulo: Universidade de São Paulo, 2002. 70p. Dissertação (Mestrado em Clínica Veterinária) - Faculdade de Medicina Veterinária e Zootecnia, 2002. 143. MARTIN, B. B. and KLIDE, A. M.. Laser AP for the treatment of chronic backpain in horses: stimulation of the AP points with a low-power laser. Veterinary Surgery. v. 16, p. 106-110, 1987. 144. MARTINEZ, R., GODOY, A., NARETTO, E., WHITE, A.. Neuroendocrine changes produced by competition stress on the Thoroughbred race horse. Compendium of Biochemical Physiology, v. 3, p. 599–602. 1988. 145. MATSSURA, A.; TANAKA, M.; IRIMAJIRI, M.; YAMAZAKI, A.; NAKANOWATARI, T.;HODATE, K. Heart rate variability after horse trekking in leading and following horses. Animal Science Journal, v. 81, p. 618–621. 2010. 146. MCBRIDE, S.D.; Mills, D.S. Psychological factors affecting equine performance. BMC Vet Res 8: 180, 2012. 147. McGREEVY, P. Equine behavior: a guide for veterinarians and equine scientists. Londres. Saunders, p. 357. 2004. 148. MEDEIROS, M. A.; MEDEIROS, N.; CANTERAS, D.; SUCHECKI A.; MELLO, L. E. A. M. “Analgesia and c-Fos expression in the PAG induced by electroacupuncture at Zusanli point in rats,” Brain Research, vol. 973, pp. 196–204, 2003. 149. MORBEG, G.P.. Biological response to stress: implications for animal welfare. In: MORBEG, G.P. & MENCH, J.A.. The biology of animal stress: basic participles and implications for animal welfare. CABI Publishing, p. 1- 22. 2000. 150. MOYNA et al. Lymphocyte Function and Cytokine Production During Incremental Exercise in Active and Sedentary Males and Females. Int J Sports Med 17 (8), p. 585-591, 1996. 151. MULLER, N.; MYINT, A.M.; SCHWARZ, M.J. Inflammatory biomarkers and depression. Neurotox. Res, v. 19, p. 308–318, 2011. 152. MUÑOZ, A.; SANTISTEBAN, R.; RUBIO, M. D.; VIVO, R.; AGÜERA, E. I; ESCRIBANO; B. M.; CASTEJÓN, F. M. The use of functional indexes to evaluate fitness in andalusian horses. Journal of Veterinary Medicine Science, v. 59, n. 9, p. 747-750, 1997. 97 153. MUNSTERS, C.; VISSER, K.; BROEK, V.D.J.; SLOET, V.O.M.M. Quantifying stress in experienced and inexperienced mounted police horses, using heart rate, heart rate variability, behavior score and suitability score. J. Vet. Behav. Clin. Appl. Res. 2013,8:e16–e17), 2013. (b) 154. MUNSTERS, C.; VISSER, K.; BROEK, V.D.J.; SLOET, V.O.M.M.; VAN, W.R. The effects of transport, riot control training and night patrols on the workload and stress of mounted police horses. Appl. Anim. Behav. Sci. 2013,143:52–60, 2013. (a) 155. NAKATA, S.; TAKEDA, F.; KUROSAWA, M. et al. Plasma adrenocorticotropin, cortisol and catecholamines responses to various exercises. Equine Vet. J.; v.30, Suplemento, p. 570-574, 1999. 156. NICOL, C.J., BADNELL-WATERS, A.J., BICE, R., KELLAND, A., WILSON, A.D., HARRIS, P.A.. The effects of diet and weaning method on the behaviour of young horses. Applied Animal Behaviour Science, v. 95, p. 205– 221. 2005. 157. NIEMAN, D.; NEHLSEN-CANNARELLA, S.; FAGOAGA, O.; HENSON, D.; UTTER, A.; DAVIS, J.; WILLIAMS, F. AND BUTTERWORTH, D. Influence of mode and carbohydrate on the cytokine response to heavy exertion. Med. Sci. Sport Exerc. 30, 671-678. 1998. 158. Nieman, D.C., Henson, D.A., Davis, J.M., Murphy, E., Jenkins, D.P., Gross, S.J.,Carmichael, M.D., Quindry, J.C., Dumke, C.L., Utter, A.C., McAnulty, S.R.,McAnulty, L.S., Triplett, N.T. and Mayer, E.P. Quercetin’s influence onexercise-induced changes in plasma cytokines and muscle and leukocyte cytokinemRNA. J. appl. Physiol. 103, 1728-1735. 2007. 159. NIEMAN, D.C.; DAVIS, J.M.; BROWN, V.; HENSON, D.A.; DUMKE, C.L.; UTTER, A.; VINCI, DOWNS, M.; SMITH, J.; CARSON, J.A.; BROWN, A.; MCANULTY, S.R. AND MCANULTY, L.S. (2004) Influence of carbohydrate ingestion on immune changes after 2 h intensive resistance training. J. appl. Physiol. 96, 1292-1298. 2004. 160. NIEMAN, D.C.; DAVIS, J.M.; HENSON, D.A.; WALBERG-RANKIN, J.; SHUTE, M.; DUMKE, C.L.; UTTER, A.C.; VINCI, D.M.; CARSON, J.A.; BROWN, A.; LEE,W.J.; MCANULTY, S.R. AND MCANULTY, L.S. Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. J. appl. Physiol. 94, 1917-1925. 2003. 161. NOBREGA, A.C. The subacute effects of exercise: concept, characteristics, and clinical implications. Exerc Sport Sci Rev. v.33, p. 84-7. 2005. 162. NOGUEIRA, G. P.; BARNABE, R. C. Is the Thoroughbred race-horse under chronic stress? Short Communication, Brazilian Journal of Medical and Biological Research, v.30, p.1237-1239, 1997. 163. NORTHOFF, H.; BERG, A. and WEINSTOCK, C.. Similarities and differences of the immune response to exercise and trauma: the IFN-gamma concept. Can. J. Physiol. Pharmacol. 76, 497-504, 1998. 164. NOSZCZYK-NOWAK, A.; BOGUCKI, S.Z.. 2015: Zmienność rytmu serca (HRV) jako nowe narzędzie diagnostyczne w medycynie weterynaryjnej (Heart rate variability (HRV) as a new diagnostic tool in veterinary medicine, in 98 Polish). Weterynaria w praktyce 6: 46-50Ostrowski, K., Rohde, T., Zacho, M., Asp, S. and Pedersen, B.K. (1998a) Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running. J. Physiol. v. 508, p. 949-953. 2015. 165. PAGAN, J.D.; GEOR, R.J.; HARRIS, P.A.; HOEKSTRA, K.; GARDNER, S.; HUDSON, C.; PRINCE; A. Effects of fat adaptationon glucose kinetics and substrate oxidation during low-intensity exercise. Equine Veterinary Journal, v.34, p.33-38, 2002. 166. PALIN, K.; PALIN, R.M.; BLUTHE, R.H.; MCCUSKER, T.; LEVADE, F.; MOOS, R.; DANTZER, K.W. The type 1 TNF receptor and its associated adapter protein FAN, arerequired for TNFalpha-induced sickness behavior. Psychopharmacology (Berl.) 201, p. 549–556, 2009. 167. PARK, H. J.; PARK, Y.; CHAE, J. W.; KIM, H.; LEE, A.; CHUNG J.H. “Effect of acupuncture on hypothalamic-pituitaryadrenal systeminmaternal separation rats,” Cellular andMolecular Neurobiology, v. 31, no. 8, p. 1123– 1127, 2 168. PEDERSEN, B.K.; HOFFMAN-GOETZ, L. Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev. v. 80, p.1055-81. 2000. 169. PELLEGRINOTTI, I. L. (Org.). Performance Humana Saúde e Esporte. Ribeirão Preto, SP: Tecmedd, p. 17-23, 2004. 170. PELTOLA, M.A. Role of editing of RR intervals in the analysis of heart rate variability, Front. Physiol. v.3. p.148. 2012. 171. PERSSON, S. D. G. On blood volume and working capacity of horses: Studies of methodology and physiological and pathological variations, Acta Physiological Scandinavica, v. 19, n. 9, p. 189, 1967. 172. PERSSON, S.G.B. Evaluation of exercise tolerance and fitness in the performance horse. In: SNOW, D.H.; PERSSON, S.G.B.; ROSE, R.J. Equine Exercise Physiology. Cambridge: Granta, 1983. p. 441-457b. PETERSEN, A.M.W.; PEDERSEN, B.K.; The anti-inflammatory effect of exercise. J. Appl. Physiol., v. 98, p. 1154-1162, 2005. 173. PICCIONE, G. et al. Differentes peridiodicities of some haematological parameters in exercise-loades athletc horses and sedentary horses. Journal Equine Science, v.12. n.1, p.17-23, 2001. 174. PITTLER, M.H.; ERNST, E. Effectiveness of Acupuncture in veterinary medicine: systematic review. Journal of Veterinary Internal Medicine, v.20, n.3, p.480-488, 2006. 175. RALSTON, S.L. Insulin and glucose regulation. Vet. Clin. Equine, v. 18, p. 295-304, 2002. 176. REDONDO, A.R; CARRANZA. J; TRIGO, P. Fat diet reduces stress and intensity of startle reaction in horses. Applied Animal Behavieour Science, v. 118, p. 69-75. 2009. 177. RIETMANN, T. R.; STAUFFACHER, M.; BERNASCONI, P.; AUER, J. A.; WEISHAUPT, M. A. The Association between Heart Rate, Heart Rate Variability, Endocrine and Behavioural Pain Measures in Horses Suffering from Laminitis.J. Vet. Med. ,v. 51 A, p.218–225. 2004a. 99 178. RIETMANN, T.R.; STUART, A.E.A.; BERNASCONI, P.; STAUFFACHER, M.; AUER, J.A.; WEISHAUPT, M.A. Assessment of mental stress in warmblood horses: heart rate variability in comparison to heart rate and selected behavioural parameters. J. Appl. Anim. Welf.Sci, v.88,p. 121–136. 2004b. 179. RIZZO, M.; ARFUSO, F.; GIANNETTO, C.; GIUDICE, E.; LONGO, F.; BRUSCHETT, D.; PICCIONE, G. Acupuncture Needle Stimulation on Some Physiological Parameters After Road Transport and Physical Exercise in Horse - Journal of Equine Veterinary Science, v. 48, 2017. 180. RIZZO, M.; ARFUSO, F.; GIANNETTO, C.; GIUDICE, E.; LONGO, F.; BRUSCHETT, D.; PICCIONE, G. Cortisol levels and leukocyte population values in transported and exercised horses after acupuncture needle stimulation - Journal of Veterinary Behavior: Clinical Applications and Research. v. 18, p. 56-61, 2017. 181. ROSE, R.J; ALLEN, J.R.; HODGSON, D.R.; STEWART, J.H.; CHANN, W. Responses to submaximal treadmill exercise and training in the horse: changes in haematology, arterial blood gas and acid base measurements, plasma biochemical values and heart rate. The Veterinary Record, v. 113, n. 26/27, p. 612-618, 1983. 182. ROSE, R. J., PURDUE, R. A., HENSLEY, W. Plasma biochemistry alterations in horses during an Endurance ride. Equine Veterinary Journal. v. 9, p. 122–126, 1977. 183. SALAHUDDIN, L.; CHO, J.; JEONG, M.G.; KIM, D.. Ultra short term analysis of heartrate variability for monitoring mental stress in mobile settings, Conference proceedings: Annual International Conference of the IEEE Engineering inMedicine and Biology Society. IEEE Eng. Med. Biol. Soc. Conference, p. 4656–4659, 2007. 184. SCHALM, O.W. Equine Hematology: the erythrocytes and plasma. Equine Practice, v. 1, n. 2, p. 37-42, 1979. 185. SCHMID, A.; KOCH, M. and SCHNITZLER, H. U.. “Conditioned pleasure attenuates the startle response in rats,” Neurobiology of Learning and Memory, v. 64, no. 1, p. 1–3, 1995. 186. SCHMIDT, A., AURICH, C., NEUHAUSER, S., AURICH, J., MÖSTL, E., Comparison of cortisol levels in blood plasma, saliva and faeces of horses submitted to different stressors or treated with ACTH. IN Symposium Equitation Science, 5, Sydney, 2009, Proceeding, p. 53. 2009. 187. SCHMIDT, A.; AURICH, J.; MÖSTL, E.; MÜLLER, J.; AURICH, C. Changes in cortisol release and heart rate and heart rate variability during the initial training of 3-year-old sport horses. Horm. Behav. 2010,58:628–636, 2010. 188. SCHMIDT, A.; MÖSTL, E.; WEHNERT, C.; AURICH, J.; MÜLLER, J.; AURICH, C. Cortisol release and heart rate variability in horses during road transport. Horm. Behav. 57:209–215, 2010 189. SCHOEN, A. M., Veterinary Acupuncture: Ancient Art to Modern Medicine, Mosby, St. Louis, Mo, USA, 2nd edition, 2001. 100 190. SCHOEN, A.M.. Acupuntura Veterinária – Da Arte Antiga à Medicina Moderna. 2ª Ed. São Paulo. Roca. 2006. 191. SCOGNAMILLO-SZABÓ, M.V.R. et al. Breve histórico da acupuntura veterinária no Brasil e sua prática no Estado de São Paulo. MEDVEP – Revista Científica de Medicina Veterinária - Pequenos Animais e Animais de Estimação, v.4, n.11, p.61-65, 2006. 192. SEEHERMAN, H.J.; MORRIS, E.; O'CALLAGHAN, M.W. The use sports medicine techniques in evaluating the problem equine athlete. Veterinary Clinics of North America-Equine Practice, v.6, n.1, p. 239-275. 1990. 193. SELYE, H. A syndrome produced by diverse nocuous agents. Nature, v. 138, p.32. 1936. 194. SIGHIERI, C.; BARAGLI, P.; VILLANI, C.; MARTELLI, F.; GATTA, D.; CIATTINI, F. Cortisolo ed insulina plasmatici nel cavallo da endurance durante test submassimale standadizzato al treadmill. Annali della Facolta di Medicina Veterinária di Pisa, v.49, p.335-343, 1996. 195. SIMÕES, H. G. Respostas metabólicas e hormonais durante os testes de determinação do limiar anaeróbio individual e lactato mínimo. Tese (Doutorado em Ciências Fisiológicas) Centro de Ciências Biológicas e da Saúde. Universidade Federal de São Carlos, 2000. 196. SNOW, D.H. et al. Post-race blood biochemistry in Troroughbred. In. SNOW, D.H.; PERSSON, S.G.B, R.J. (Eds.). Equine exercise physiology. p. 389- 399. 1983 197. DER, J; R JER, J. T. and NOSTELL, K.E.A. Interday variation and effect of transportation on indirect blood pressure measurements, plasma endothelin-1 and serum cortisol in Standardbred and Icelandic horses.Acta Veterinaria Scandinavica, 54:37, 2012. 198. SOLIGO, M.; NORI, S. L. L.; PROTTO, V.; FLORENZANO, F., MANNI, L. Acupuncture and neurotrophinmodulation, in Neurobiology ofAcupuncture: 111 International Review of Neurobiology, B.-Y. Zeng, K. Zhao, and F.-R. Liang, Eds.; Academic Press, London, UK, 2013. Q.-Q. Li, G.-X. Shi, Q. Xu, J. Wang, C.-Z. Liu, and L.-P. Wang, “Acupuncture effect and central autonomic regulation,” Evidence- Based Complementary and Alternative Medicine, v. 2013, 6 pages, 2013. 199. STAUSS, H. M.. Heart rate variability. AJP- Regul. Integ. Comp. Physiol., v.285, p. R927 - R931, 2003. 200. STRELTSOVA et al.. Effect of orange peel and black tea extracts on markers of performance and cytokine markers of inflammation in horses. Equine and Comparative Exercise Physiology, v.3, p. 121-130, 2006. 201. Strzelec, K.; Kankofer, M.; Pietrzak, S.. Cortisol concentration in the saliva of horses subjected to different kinds of exercise. Acta Veterinaria Brno, 2011. 202. Suuager, J.K. et al. Relationships between Body Condition Score and Plasma Inflammatory Cytokines, Insulin, and Lipids in a Mixed Population of Light-Breed Horses. Journal of Veterinary Internal Medicine, v. 27, p. 157- 163, 2013. 101 203. TAKAHASHI, T. “Mechanismof acupuncture on neuromodulation in the gut—a review,” Neuromodulation: Technology at the Neural Interface, v. 14, no. 1, p. 8–12, 2011. 204. TASK-FORCE, 1996. Heart rate variability: standards of measurement physiological interpretation, and clinical use. Task Force of the European Society of Cardiology the North American Society of Pacing. Circulation 93,1043– 1065, 1996. 205. TEIXEIRA, P. P. e PADUA, J. T.. Avaliação dos níveis de cortisol, tiroxina, triiodotironina e glicose como indicativos de estresse em cavalos puro sangue inglês de corrida, antes e após a competição. Ciência Animal Brasileira, v. 3, n. 1, p. 39-48. 2002. 206. TENNENT-BROWN, B. S.. Lactate production and measurement in critically ill horses. Compendium on Continuing Education for the Practising Veterinarian, 33(12), E5, 2011. 207. TIRGOVISTE, C.I.. Anatomic and functional particularities of skin areas used in acupuncture. Am J Acupunct, v. 3, p.199-206. 1975. 208. ULRICH-LAI, Y. M.; HERMAN, L. P. Neural regulation of endocrine and autonomic stress responses. Nature Reviews Neuroscience, v.10, p. 397-409. 2009. 209. VAN BREDA, E. A Nonnatural Head–Neck Position(Rollkur) During Training Results in Less Acute Stress in Elite, Trained, Dressage Horses. Journal of Applied Animal Welfare Science, v. 9, issue 1, 2006. 210. VAN ERCK et al. Evaluation of oxygen consumption during field exercise tests in Standardbred trotters. Equine and Comparative Exercise Physiology, v.4, p. 43–49, 2007. 211. VANDERLEI, L. C. M., PASTRE, C.M., HOSHI, R.A., CARVALHO, T.D, GODOY, M.F. Noções Básicas de Variabilidade da Frequência Cardíaca e sua aplicabilidade Clínica. Ver. Bras. Cir. Cardiovasc, v. 24, n. 2, p. 205-217. 2009. 212. VELLUCI, S. V. The autonomic and behavioral responses to stress. Stress, Stress Hormones and the Immune System, London: Wiley, 1997. p.64-65, 1997. 213. VILA, J.; GUERRA, P.; MUNOZ, M.A.; VICO, C.; VIEDMA-DEL JESUS, M.I.; DELGADO, L.C.; PERAKAKIS, P.; KLEY, E.; MATA, J.L.; RODRIGUEZ, S.. Cardiac defense: fromattention to action. Int. J. Psychophysiol. 66, 169–182, 2007. 214. VILLAS- OA , J. D.; DIA , D. P. M.; MEDEIRO , M. A. “Experimental model of startle in horses,” in Proceedings of the International Workshop in Neuroendocrinology, 2016. 215. VILLAS-BOAS, J.D.; DIAS, D.P.M.; TRIGOC, P.I.; DOS SANTOS ALMEIDA, N.A.; DE ALMEIDA, F.Q.; DE MEDEIROS, M.A. Behavioural, endocrine and cardiac autonomic responses to a model of startle in horses. Appl. Anim. Behav. Sci. 2015. 216. VISSER, E.K., REENEN, C.G., HOPSTER, H., SCHILDER, M.B.H., KNAAP, J.H., BARNEVELD, A., BKOHUIS, H.J.. Quantifying aspects of young 102 horses’s temperament: consistency of behavioural variable. Applied Animal Behaviour Science, v. 74, p. 241–258. 2001. 217. VISSER, E.K.; VAN REENEN, C.G.; VAN DER WERF, J.T.; SCHILDER, M.B.; KNAAP, J.H.; BARNEVELD, A.; BLOKHUIS, H.J. Heart rate and heart rate variability during a novel object test and a handling test in young horses. Physiol. Behav. v. 76, p. 289–296, 2002. 218. VOGEL, J. H. K.; BOLLING, S. F.; COSTELLO, R. B. “Integrating complementary medicine into cardiovascular medicine: a report of the American college of cardiology foundation task force on clinical expert consensus documents (Writing Committee to Develop an Expert Consensus Document on Complementary and IntegrativeMedicine),” Journal of the American College of Cardiology, v. 46, no. 1, p. 184–221, 2005. 219. VON BORELL, E.; LANGBEIN, J.; DESPRÉS, G.; HANSEN, S.; LETERRIER, C.; MARCHANT-FORDE, J.; VEISSIER, I. Heart rate variability as a measure of autonomic regulation of cardiac activity for assessing stress and welfare in farm animals—a review. Physiol Behav, v. 92, p. 293-316, 2007. 220. WANG, J. D.; KUO, T. B. J.; YANG, C. C. H. “An alternative method to enhance vagal activities and suppress sympathetic activities in humans,” Autonomic Neuroscience: Basic and Clinical, v. 100, no. 1-2, p. 90–95, 2002. 221. WANG, S.J.; ZHANG, J.J.; YANG, H.Y.; F. WANG, S.T. Acupoint specificity onacupuncture regulation of hypothalamic- pituitary-adrenal cortex axisfunction. BMC Complement Altern. Med. 27 (2015) 87, 2015. 222. WANG, Z. L.; WANG, C.; MAK, A. F.T.; CHOW, H. K. “Effects of acupuncture on heart rate variability in normal subjects under fatigue and non-fatigue state,” European Journal of Applied Physiology, v. 94, no. 5-6, p. 633–640, 2005. 223. WELLHOENER, P.; BORN, J.; FEHM, H.L.; DODT, C. Elevated resting and exercise-induced cortisol levels after mineralocorticoid receptor blockade with canrenoate in healthy humans. J Clin Endocrinol Metab, v. 89, p. 5048–5052. 2004. 224. WILK, I.; JANCZAREK, I.. Relationship between behavior and cardiac response to round pen training. J Vet Behav, v. 10, p. 231-236, 2015. 225. WILK, I.; KĘDZIER KI, W.; TACHUR KA, A.; JANCZAREK, I.. Are results of Crib Opening Test connected with efficacy of training horses in a round-pen? Appl Anim Behav Sci, v. 166, p. 89-97, 2015. 226. XIE, H.; LIU, H. Equine back pain: a tradicional chinese medical review. The Veterinary clinics of North America. Equine practice, Philadelphia, v. 19, p. 6-12, 1997. 227. YAMAMURA ,Y. Acupuntura-Tradicional :a Arte de Inserir. Roca, São Paulo. 1993. 228. YANG ,C. H.; LEE, B. B.; JUNG, H. S.; SHIM, I.; ROH, P. U.; GOLDEN, G. T. “Effect of electroacupuncture on response to immobilization stress,” Pharmacology Biochemistry and Behavior, v. 72, no. 4, p. 847–855, 2002. 229. YOU, Z.; LUO, C.; ZHANG, W.; CHEN, Y.; HE, J.; ZHAO, Q.; ZUO, R.; WU, Y. Pro- andanti-inflammatory cytokines expression in rat’s brain and spleen exposed tochronic mild stress: involvement in depression, Behav. Brain Res., v. 225, p. 135–141, 2011. 230. YUN, S.J., PARK, H.J., YEOM, M.J., HAHN, D.H., LEE. H.J., LEE, E.H. Effect of electroacupuncture on stress-induced changes in brain-derived neurotrophic factor expression in rat hippocampus. Neurosci. Lett., v. 318, p. 85-88. 2002.por
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