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dc.contributor.authorAndriotti, Paula Azevedo
dc.date.accessioned2023-12-22T02:58:44Z-
dc.date.available2023-12-22T02:58:44Z-
dc.date.issued2020-02-20
dc.identifier.citationANDRIOTTI, Paula Azevedo. Eficácia do Sarolaner no tratamento de miíases em cães causadas por Dermatobia hominis (Diptera: Cutebridae). 2020. 46 f. Dissertação (Mestrado em Medicina Veterinária, Ciências Clínicas) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, 2020.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/14277-
dc.description.abstractAs lesões causadas por bernes são bastante desconfortáveis e dolorosas para os cães, podendo causar infecções bacterianas secundárias e predispor a outras miíases. Um tratamento eficaz deve eliminar ou matar as larvas existentes e promover a cicatrização da ferida o mais precoce possível. Entretanto, atualmente, o tratamento recomendado para esse parasito consiste na retirada manual das larvas, o que causa muito desconforto para o animal parasitado, tanto que, em alguns casos, há a necessidade de sedação para realização do procedimento. O objetivo deste estudo foi avaliar a eficácia bernicida do sarolaner para o tratamento de Dermatobia hominis em cães naturalmente infestados. Foram incluídos dez cães, sem raça definida, com idade variando entre dois e seis anos, independente da variável sexo, com peso entre 11,4 e 19,1 kg, com no mínimo três larvas. No total foram contabilizadas 75 larvas, com média de 7,5 larvas por animal. A maior parte do parasitismo (46 larvas) estava localizado na região lateral dos animais. Os animais foram medicados com sarolaner na dose de 2,0 mg/kg, administrado por via oral em dose única, seguindo as recomendações em bula para o tratamento de outras ectoparasitoses. Após o tratamento, os animais foram mantidos em seus domicílios e foram feitas observações para verificar a atividade de eliminação e o efeito bernicida do fármaco após 24 horas da administração da medicação. Foi considerada larva viva qualquer parasito que apresentasse motilidade após remoção mecânica. Como critérios de avaliação da eficácia do sarolaner, o efeito larvicida foi calculado para cada animal pela fórmula: [Número de larvas vivas após o tratamento – número de larvas vivas antes do tratamento) / Número de larvas vivas antes do tratamento] × 100. Após 24 horas da administração da medicação todas as larvas foram encontradas mortas, ainda que localizadas na derme dos animais. Nenhum animal apresentou efeito adverso ou alteração do comportamento após a utilização da isoxazolina. Conclui-se que o sarolaner administrado em dose única de 2,0mg/kg, por via oral, foi 100% eficaz em cães naturalmente infestados por D. hominis.por
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpor
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectbernepor
dc.subjectsarolanerpor
dc.subjectlarvicidapor
dc.subjectlarvicideeng
dc.titleEficácia do Sarolaner no tratamento de miíases em cães causadas por Dermatobia hominis (Diptera: Cutebridae)por
dc.title.alternativeEfficacy of Sarolaner in the treatment of myiasis in dogs caused by Dermatobia hominis (Diptera: Cutebridae)eng
dc.typeDissertaçãopor
dc.description.abstractOtherLesions caused by breeds are quite uncomfortable and painful for dogs, and can cause secondary bacterial infections and predispose to other myiasis. Effective treatment should eliminate or kill existing larvae and promote wound healing as early as possible. However, currently, the recommended treatment for this parasite consists of manual removal of the larvae, which causes a lot of discomfort for the parasitized animal, so much so that, in some cases, there is a need for sedation to perform the procedure. The aim of this study was to evaluate the bernicidal efficacy of sarolaner for the treatment of Dermatobia hominis in naturally infested dogs. Ten mongrel dogs were included, aged between one and ten years, regardless of the sex variable, weighing between 11.4 and 19.1 kg, with at least three larvae. In total 75 larvae were counted, with an average of 7.5 larvae per animal. Most of the parasitism (46 larvae) was located in the lateral region of the animals. The animals were medicated with sarolaner at a dose of 2.0 mg / kg, administered orally in a single dose, following the recommendations in the package insert for the treatment of other ectoparasitoses. After treatment, the animals were kept in their homes and observations were made to verify the elimination activity and the bernicidal effect of the drug after 24 hours of medication administration. Any parasite that showed motility after mechanical removal was considered a live larva. As criteria for assessing the efficacy of sarolaner, the larvicidal effect was calculated for each animal using the formula: [Number of live larvae after treatment - number of live larvae before treatment) / Number of live larvae before treatment] × 100. After 24 hours after medication administration, all larvae were found dead, although located in the animals' dermis. No animal had an adverse effect or behavior change after using isoxazoline. It is concluded that sarolaner administered in a single dose of 2.0mg / kg, orally, was 100% effective in dogs naturally infested by D. hominis.eng
dc.contributor.advisor1Fernandes, Júlio Israel
dc.contributor.advisor1ID082.100.187-60por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/9221592908532393por
dc.contributor.referee1Fernandes, Júlio Israel
dc.contributor.referee2Balthazar, Daniel de Almeida
dc.contributor.referee3Cirne, Lilian Cristina de Souza Oliveira Batista
dc.creator.ID140.711.147-70por
dc.creator.Latteshttp://lattes.cnpq.br/9447255004002929por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Medicina Veterinária (Patologia e Ciências Clínicas)por
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dc.subject.cnpqMedicina Veterináriapor
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