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dc.contributor.authorMelo, Raquel Moreira Pires dos Santos
dc.date.accessioned2023-12-22T02:00:40Z-
dc.date.available2023-12-22T02:00:40Z-
dc.date.issued2011-03-30
dc.identifier.citationMELO, Raquel Moreira Pires dos Santos. Eficácia do Fipronil Oral e do Nitempiram Oral e Tópico no Controle de Ctenocephalides felis felis em Cães. 2011. 68 f. Tese (Programa de Pós-Graduação em Ciências Veterinárias) - Universidade Federal Rural do Rio de Janeiro, Seropédica.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/12010-
dc.description.abstractOs objetivos do presente estudo foram avaliar a eficácia de diferentes concentrações e formulações do fipronil e de nitempiram no controle de Ctenocephalides felis felis em cães. Os animais utilizados pertenciam ao Laboratório de Quimioterapia Experimental em Parasitologia Veterinária (LQEPV), do Departamento de Parasitologia Animal, Instituto de Veterinária, da Universidade Federal Rural do Rio de Janeiro. Os espécimes de C. f. felis utilizados nas infestações artificiais foram provenientes da colônia mantida no LQEPV. A eficácia pulicida de formulações de uso tópico de nitempiram 10% em cães foi de 100% do dia +2 ao dia +21, para os dias +28, +35, +42 e +49 as eficácias foram de 99,59; 96,89; 92,70 e 65% respectivamente A eficácia pulicida de formulações de uso tópico de nitempiram 15% em cães foi de 100; 99,78; 100; 100; 99,59; 98,80; 94,96 e 76,09% para os dias +2, +7, +14, +21, + 28, +35, +42 e +49 respectivamente. Para o grupo que recebeu a formulação tópica de nitempiram a 20% a eficácia foi de 100% do dia +2 ao dia +28 e de 99,76; 98,49 e 89,35 para os dias +35, +42 e +49 respectivamente. Tais formulações demonstraram que o nitempiram quando administrado topicamente nas concentrações supracitadas obteve níveis satisfatórios de eficácia e prolongado período residual contra reinfestações por C. f. felis. Para o estudo que avaliou o nitempiram administrado por via oral no controle de C. f. felis em cães a formulação a 1% (1mg.kg-1) apresentou eficácia no dia +2 de 100% e no dia +7 foi de 24,29%. A formulação de uso oral com nitempiram a 5% (5mg.kg-1) a eficácia foi de 100% para o dia +2 e 57,01% para o dia +7. Quando o nitempiram foi administrado por via oral a 10% (10mg.kg-1) a eficácia foi de 100; 91,59 e 61,45% para os dias +2, +7 e +14 respectivamente. O nitempiram quando administrado por via oral demonstrou eficácia pulicida por um período reduzido, não apresentado período residual curto. Para o estudo realizado com o fipronil administrado por via oral no controle de C. felis felis em cães a formulação com 2mg.kg-1 apresentou eficácia no dia +2 de 100% e no dia +7 de 83,79%. Quando o fipronil foi administrado por via oral na dose de 4mg.kg-1 a eficácia foi de 88,34 para o dia +2 e 67,98 para o dia +7. O fipronil fornecido por via oral na dose de 6mg.kg-1 teve eficácia de 97,88, 95,27, 88,75 e 71,43% para os dias +2, +7, +14 e +21 respectivamente. Por tanto o fipronil quando administrado por via oral em cães apresentou eficácia limitada no controle de C. f. felis, não sendo indicado para um controle a longo prazo, podendo ser indicado para eliminações rápidas de pulgas sobre o hospedeiro.por
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de nível Superior - CAPESpor
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJpor
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico - CNPqpor
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectpulgaspor
dc.subjectnitempirampor
dc.subjectfipronilpor
dc.subjectcãespor
dc.subjectfleaseng
dc.subjectnitenpyrameng
dc.subjectfipronileng
dc.subjectdogseng
dc.titleEficácia do Fipronil Oral e do Nitempiram Oral e Tópico no Controle de Ctenocephalides felis felis em Cãespor
dc.title.alternativeEfficacy of Oral Fipronil and Oral and Topic Nitenpyram in the Control of Ctenocephalides felis felis in Dogseng
dc.typeTesepor
dc.description.abstractOtherThe objectives of this study were to evaluate the efficacy of different concentrations and formulations of fipronil and nitenpyram in the control of Ctenocephalides felis felis in dogs. The animals used belonged to the Laboratório de Quimioterapia Experimental em Parasitologia Veterinária (LQEPV), Departamento de Parasitologia Animal, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro. Specimens of C. f. felis used in the infestations were from the colony maintained in LQEPV. The pulicide efficacy of topical formulations of nitenpyram 10% in dogs was 100% of the day +2 to day +21. On days +28, +35, +42 and +49 efficiencies were 99.59, 96, 89, 92.70 and 65% respectively. The pulicide efficacy of topical formulations of nitenpyram 15% in dogs was 100, 99.78, 100, 100, 99.59, 98.80, 94.96 and 76 09% for days +2, +7, +14, +21, +28, +35, +42 and +49 respectively. For the group that received topical formulation nitenpyram 20% the pulicide efficiency was 100% of the day +2 to day +28 and 99.76, 98.49 and 89.35 for the day +35, +42 and +49 respectively. Such formulations of nitenpyram demonstrated that when administered topically at concentrations above obtained satisfactory levels of efficacy and long residual period against reinfestation by C. f. felis. For the study that assessed the nitenpyram administered orally in control of C. f. felis in dogs the formulation of 1% (1mg.kg-1) showed an efficacy of 100% on day +2 and day +7 was 24.29%. The formulation of administered orally 5% (5mg.kg-1) the efficacy was 100% for day +2 and 57.01% for the day +7. When nitenpyram was administered orally 10% (10mg.kg- 1) the efficacy was 100, 91.59 and 61.45% for days +2, +7 and +14 respectively. The nitenpyram when administered orally demonstrated pulicide efficacy for a short period, not to have residual period. For the study of fipronil administered orally in control of C. f. felis in dogs with the formulation 2mg.kg-1 showed an efficacy of 100% on day +2 and day +7 was 83.79%. When fipronil was administered orally at a dose of 4mg.kg-1efficacy was 88.34 to 67.98% for day +2 and day +7 respectively. Fipronil provided orally at a dose of 6mg.kg-1 was effective in 97.88, 95.27, 88.75 and 71.43% for days +2, +7, +14 and +21 respectively. Therefore fipronil when administered orally in dogs has limited efficacy in control of C. f. felis, and is not suitable for a long-term control, may be suitable for rapid elimination of fleas on the host.eng
dc.contributor.advisor1Scott, Fabio Barbour
dc.contributor.advisor1ID001.382.167-97por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/1217253540572819por
dc.contributor.referee1Scott, Fabio Barbour
dc.contributor.referee2Tancredi, Ian Philippo
dc.contributor.referee3Martins, Isabella Vilhena Freire
dc.contributor.referee4Moya Borja, Gonzalo Efrain
dc.contributor.referee5Grisi, Laerte
dc.creator.ID093.496.257-09por
dc.creator.Latteshttp://lattes.cnpq.br/0387963542253661por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Ciências Veterináriaspor
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