Please use this identifier to cite or link to this item:
https://rima.ufrrj.br/jspui/handle/20.500.14407/17609Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Castro, Wladymir Mendes Carvalho de | - |
| dc.date.accessioned | 2024-07-09T15:51:52Z | - |
| dc.date.available | 2024-07-09T15:51:52Z | - |
| dc.date.issued | 2022-08-02 | - |
| dc.identifier.citation | CASTRO, Wladymir Mendes Carvalho. Avaliação in vitro do óleo essencial de Caesalpinia pulcherrima(L)Sw. contra estágios imaturos e adultos de Ctenocephalides felis felis. 2022. 79 f. Dissertação (Mestrado em Química) - Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, 2022. | pt_BR |
| dc.identifier.uri | https://rima.ufrrj.br/jspui/handle/20.500.14407/17609 | - |
| dc.description.abstract | A interação entre humanos e animais tem aumentado cada vez mais, e com isso, eleva- se a preocupação em relação à saúde desses animais. Gatos e cachorros estão suscetíveis à infestação por carrapatos e pulgas, sendo o Rhipicephalus sanguineus e Ctenocephalides felis felis os mais comuns. A pulga do gato, conhecida como C. felis felis, é um inseto hematófago, sem asas que parasita os animais domésticos, que necessitam de alimentação diária. Deste modo, os animais sofrem constantemente com irritações cutâneas, anemias e dermatites alérgicas. Diante do desenvolvimento de resistência desses insetos frente ao tratamento com produtos químicos, os óleos essenciais mostram-se como alternativas promissoras, visto que já possuem atividade descrita contra alguns insetos. Sabendo-se desse potencial dos óleos essenciais, o presente trabalho tem como objetivo extrair o óleo essencial de C. pulcherrima, identificar seus componentes, avaliar sua atividade inseticida contra adultos e estágios imaturos da pulga do gato. Foram realizados testes in vitro de screening, para avaliar o comportamento das pulgas frente ao óleo essencial, em 10 concentrações diferentes no período de 24 e 48 horas utilizando-se 10 pulgas. Utilizou-se a técnica de impregnação em papel filtro. O óleo essencial de C. pulcherrima é rico em germacreno D (47,04 %) e apresentou atividade contra C. felis. Contra adultos, foi possível observar mortalidade de 15% e 40% a 800 μg cm-2 , no período de 24 e 48 horas, respectivamente. Contra ovos e pupas, observou-se 100% de mortalidade na concentração máxima (800 μg cm-2 ); já contra larvas, observou-se mortalidade máxima a 400 μg cm-2 em ambos os tempos testados. Testou-se também a atividade do óleo essencial, em duas concentrações, na inibição da enzima acetilcolinesterase, mas não foi possível observar esta inibição frente às duas concentrações analisadas. O óleo essencial estudado apresentou atividade significativa tanto para adultos quanto para os estágios imaturos de C. felis concluindo- se que possa ser um ótimo candidato para o controle de pulgas, sendo utilizado como uma alternativa para o desenvolvimento de pulicidas naturais. | pt_BR |
| dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES | pt_BR |
| dc.language | por | pt_BR |
| dc.publisher | Universidade Federal Rural do Rio de Janeiro | pt_BR |
| dc.subject | óleos essenciais | pt_BR |
| dc.subject | pulicidas | pt_BR |
| dc.subject | testes in vitro | pt_BR |
| dc.subject | essential oils | pt_BR |
| dc.subject | pulicidal | pt_BR |
| dc.subject | in vitro tests | pt_BR |
| dc.title | Avaliação in vitro do óleo essencial de caesalpinia pulcherrima (L.) Sw. contra estágios imaturos e adultos de ctenocephalides felis felis | pt_BR |
| dc.title.alternative | In vitro evaluation of the essential oil of caesalpinia pulcherrima (L.) Sw. against immature and adult stages of ctenocephalides felisfelis | en |
| dc.type | Dissertação | pt_BR |
| dc.description.abstractOther | The interaction between humans and animals has increased more and more, and with that, the concern about the health of these animals increases. Cats and dogs are susceptible to tick and flea infestation, with Rhipicephalus sanguineus and Ctenocephalides felis felis being the most common. The cat flea, known as C. felis felis, is a hematophagous, wingless insect that parasitizes domestic animals that need daily food. In this way, animals are constantly suffering from skin irritations, anemia and allergic dermatitis. Given the development of resistance of these insects to treatment with chemical products, essential oils show themselves as promising alternatives, as they already have described activity against some insects. Knowing this potential of essential oils, the present work aims to extract the essential oil from Caesalpinia pulcherrima, identify its components, evaluate its insecticidal activity against adults and immature stages of cat flea. In vitro screening tests were carried out to evaluate the behavior of fleas against the essential oil, at 10 different concentrations in the period of 24 and 48 hours, using 10 fleas. The technique of impregnation on filter paper was used. The essential oil of C. pulcherrima is rich in germacrene D (47.04%) and has activity against C. felis. Against adults, it was possible to observe mortality between 15% and 40% at 800 μgcm-2 , in the period of 24 and 48 hours, respectively. Against eggs and pupae, 100% mortality was observed at the maximum concentration (800 μgcm-2 ); against larvae, maximum mortality was observed at 400 μgcm-2 in both times tested. The activity of the essential oil was also tested, in two concentrations, in the inhibition of the acetylcholinesterase enzyme, but it was not possible to observe this inhibition in the two analyzed concentrations. The essential oil studied showed significant activity for both adults and immature stages of C. felis, concluding that it may be a great candidate for flea control, being used as an alternative for the development of natural pulicidal. | en |
| dc.contributor.advisor1 | Chaves, Douglas Siqueira de Almeida | - |
| dc.contributor.advisor1Lattes | http://lattes.cnpq.br/1864237318361425 | pt_BR |
| dc.contributor.referee1 | Chaves, Douglas Siqueira de Almeida | - |
| dc.contributor.referee1Lattes | http://lattes.cnpq.br/1864237318361425 | pt_BR |
| dc.contributor.referee2 | Salles, Cristiane Martins Cardoso de | - |
| dc.contributor.referee2Lattes | http://lattes.cnpq.br/3610279707231709 | pt_BR |
| dc.contributor.referee3 | Fingolo, Catharina Eccard | - |
| dc.contributor.referee3Lattes | http://lattes.cnpq.br/3921610346020676 | pt_BR |
| dc.creator.Lattes | http://lattes.cnpq.br/9230229346299288 | pt_BR |
| dc.publisher.country | Brasil | pt_BR |
| dc.publisher.department | Instituto de Química | pt_BR |
| dc.publisher.initials | UFRRJ | pt_BR |
| dc.publisher.program | Programa de Pós-Graduação em Química | pt_BR |
| dc.relation.references | ABDEL-RAHMAN, A.; DECHKOVSKAIA, A.M.; GOLDSTEIN, L.B.; BULLMAN, S.H.; KHAN, W.; EL-MASRY, E.M.; MOHAMED, B. Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats. Journal of Toxicology and Environmental Health Part A, v.67,n.4, pp 331-356, 2004. ABDEL-RAHMAN, A.; SHETTY, A.K.; ABOU-DONIA, M.B. Subchronic dermal application of N,N-diethyl-m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the cerebellum. Experimental Neurology, v.172,n.1, pp 153-171, 2001. ABOU-DONIA, M.B.; GOLDSTEIN, L.B.; DECHKOVSKAIA, A.; BULLMAN, S.; JONES, K.H.; HERRICK, E.A.; ABDEL-RAHMAN, A.A.; KHAN, W.A. Effects of daily dermal application of DEET and epermethrin, alone and in combination, and sensorimotor performance, blood-brain barrier, and blood-testis barrier in rats. Journal of Toxicology and Environmental Health Part A, v.62,n.7, pp 523-541, 2001. ABOU-DONIA, M.B.; GOLDSTEIN, L.B.; JONES, K.H.; ABDEL-RAHMAN, A.A.; DAMODARAN, T.V.; DECHKOVSKAIA, A.M.; BULLMAN, S.L.; AMIR, B.E.; KHAN, W.A. Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. Toxicological Sciences, v.60, pp 305-314, 2001b. ADAMS, R. P. Identification of essential oil components by gas chromatography/mass spectroscopy. 4. ed. Carol Stream: Allured Publishing Corporation, 2007. ADEWUYI, A.& ODERINDE, R.A. Fatty acid composition and lipid profile of Diospyros mespiliformis, Albizia lebbeck, and Caesalpina pulcherrima seed oils from Nigeria. InternationalJournalof Food Science, ID 283616, pp 1-6, 2014. AZEVEDO, A.M.A.; JUNIOR, S.P.A,; CARVALHO, G. M.; Mário,; ARAÚJO, F. T. & JUNIOR, C.A.E.F Chemical Composition of Flowers Essential Oils of Four Varieties from Caesalpinia pulcherrima (L) W, Journal of Essential Oil Bearing Plants, 21:4, 987-993, 2018. DOI: 10.1080/0972060X.2018.152612 AKTER, K.; BARNES, E.C.; LOA-KUM-CHEUNG, W.L.; YIN, P.; KICHU, M.; BROPHY, J.J.; BARROW, R.A.; IMCHEN, I.; VEMUPALD, S.R.; JAMIE, J.F. Atividade antimicrobiana e antioxidante e caracterização química de Erythrinastricta Roxb. (Fabaceae).JournalofEthnopharmacology, v.185,pp 171- 181, 2016. https://doi.org/10.1016/j.jep.2016.03.011 ALMEIDA, L.F.R.; DELACHIAVE, M.E.A.; MARQUES, M.O.M. Composição do óleo essencial de rubim (Leonurussibiricus L. - Lamiaceae). Revista Brasileira de Plantas Medicinais, v.8, n.1, pp 35-8, 2005. ANVISA. FarmacopéiaBrasileira.Volume 2. 6a edição. Brasília: Ministério da Saúde, 2019. 62 ARYA, A., C, R., RAO, R., RAHMAN, M., KAUSHIK, D., AKHTAR, M. F., SALEEM, A., KHALIFA, S., EL-SEED, H., ALBADRANI, G., ABDEL D. M., MITTAL, V. Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy. Biomolecules. 11. 10.3390/biom11030350, (2021). ASKARY, M.; TALEBI, S.M.; AMINI, F.; BANGAN, A.D.B. Effect of NaCl and iron oxide nanoparticles on Mentha piperita essential oil composition. Environmental and Experimental Biology, v.14, pp 27-32, 2016. ATSDR. Toxicological profile for DEET (N,N-diethyl-meta-toluamide). U.S. Department of Health and Human Services. Agency for Toxic Substances and Disease Registry, 2017. https://www.atsdr.cdc.gov/ToxProfiles/tp185.pdf. Acessoem 20 de abril de 2022. BACHOVCHIN, D. A.; CRAVATT, B. F. The pharmacological landscape and therapeutic potential of serine hydrolases. Nature Reviews Drug Discovery, v. 11, n. 1, p. 52–68, 2012. BALADANIDOU, V.; GRIGORALI, L.; VONTAS, J. Insectcuticle: a criticaldeterminantofinsecticideresistance. Current Opinion in Insect Science, v.27, pp 68-74, 2018. BALDIN, E.L.L.; AGUIAR, G.P.; FANELA, T.L.M.; SOARES, M.C.E.; GROPPO, M.; CROTTI, A.E.M.Bioactivity of Pelargonium graveolens essential oil and related monoterpenoids against sweet potato whitefly, Bemisiatabacibiotype B. Journal of Pest Science, v.88, n.1, pp 191–199, 2014. BARREIRO, E.J.& FRAGA, C.A.M. Química Medicinal: as bases moleculares da ação dos fármacos. 3a edição. Porto Alegre: Editora ArtMed, 2015. 590p. BASSOLÉ, I.H.N. and JULIANI, H.R., 2012. Essential oils in combination and their antimicrobial properties. Molecules, vol. 17, no. 4, pp. 3989-4006. http://dx.doi.org/10.3390/molecules17043989 PMid:22469594. BATISTA, L.C.S.O.; CID, Y.P.; ALMEIDA, A.P.; PRUDÊNCIO, E.R.; RIGER, C.J.; SOUZA, M.A.A.; COUMENDOUROS, K.; CHAVES, D.S.A.InvitroefficacyofessentialoilsandextractsofSchinus mole L. Against Ctenocephalidesfelisfelis. Parasitology, v.143, n.5, pp 627–638, 2016. BAYER 2021: Pulga de gato. Bayer BayerCropScience, Portugal. Disponível em: https://www.environmentalscience.bayer.pt/pest-management/o-que-controlar/cat- flea. Acesso em 10 de novembro de 2021. BENCHAA, S.; HAZZIT, M.; ABDELKRIM, H. Allelopathic effect of Eucalyptus citriodora essential oil and its potential use of bioherbicide. Chemistry & Biodiversity, v.15, pp e1800202, 2018. 63 BENELLI, G. & PAVELA, R. Beyond mosquitoes—Essential oil toxicity and repellency against bloodsucking insects. Industrial Crops and Products, v.117, pp 382– 392, 2018. BRENNER, G. M., CRAIG W. S. Farmacologia. 4 edição, Elsevier Health Sciences, 2012. BULLOW, N.& KÖNIG, W.A. The role of germacrene D as a precursor in sesquiterpene biosynthesis: investigations of acid catalyzed, photochemically and thermally induced rearrangements. Phytochemistry, v. 55,n.2, pp 141-168, 2000. BURČUL, F.; BLAŽEVIĆ, I.; RADAN, M.; POLITEO, O. Terpenes, phenylpropanoids, sulfur and other essential oils constituents as inhibitors of cholinesterases. Current Medicinal Chemistry, v.27, n.26, pp 4297-4343, 2020. BURITI, F.C.A.; FREITAS, S.C.; EGITO, A.S.; SANTOS, K.M.O. Effects of tropical fruit pulps and partially hydrolysed galactomannan from Caesalpinia pulcherrima seeds on the dietary fibre content, probiotic viability, texture and sensory features of goat diary beverages. LWT – Food Science and Technology, v,59, pp 196-203, 2014. CDC. https://www.cdc.gov/index.htm, com os inseticidas organofosforados disponíveis em https://www.cdc.gov/nceh/clusters/fallon/organophosfaq.htm#:~:text=Organophosphat es%20are%20a%20group%20of,that%20poison%20insects%20and%20mammals.&te xt=Organophosphate%20insecticides%20. Acesso em 20 de abril de 2022. CDC. https://www.cdc.gov/lyme/removal/index.html. Acesso em 20 de abril de 2022. CHAIEB, K.; HAJLAOUI, H.; ZMANTAR, T.; KAHLA-NAKBI, A.B.; ROUABHIA, M.; MAHDOUANI, K.; BAKHROUF, A. The Chemical compositionandbiologicalactivityofcloveessentialoil, Eugenia caryophyllata (SyzigiumaromaticumL. Myrtaceae): a short review. Phytotherapy Research, v.21, pp 501-506, 2007. CHANDRA, M.; PRAKASH, O.; KUMAR, R.; BACCHETTI, R.K.; BHUSHAN, B.; KUMAR, M.; PANT, A.K. β-Selinene-Rich Essential Oils from the Parts of Callicarpa macrophylla and Their Antioxidant and Pharmacological Activities. Medicines, v.4,n.2, pp 52, 2017. https://doi.org/10.3390/medicines4030052 CHICHIOCO-HERNANDEZ, C.L. & LEONIDO, F.M.G. Weight-lowering effects of Caesalpinia pulcherrima, Cassia fistula and Senna alataleaf extracts. Journal of Medicinal Plants Research, v.5,n.3, pp 452-455, 2011. CHOUDHARY, M. I. "Produtos naturais bioativos como fonte potencial de novos farmacoprópios. Uma teoria da memória." Química Pura e Aplicada 73.3 pp, 555-560, (2001). CLARK, A.G.& SHAMAAN, N.A. Evidence that DDT-dehydrochlorinase from the house fly is a glutathione-S-transferase. Pesticide Biochemistry and Physiology, v.22,n.3, pp 249-261, 1984. 64 COLES, T.B.& DRYDEN, M.W. Insecticide/acaricide resistance in fleas and ticks infesting dogs and cats. Parasites and Vectors, v.7, n.1, pp 1–10, 2014. COLOVIC ́, M.B, KRSTIC ́ D.Z, LAZAREVIC ́-PASTI T.D, BONDZIC ́ A.M, VASIC ́ V.M. Inibidores de acetilcolinesterase: farmacologia e toxicologia. Curr Neuropharmacol. 11(3):315-35, Maio: 2013. CONSTANI, N.R.R., SOETJPITO, H. e HARTINI, S. "Atividade Antibacteriana e Composição Química da Flor do Pavão Vermelho (Caesalpinia pulcherrima L.) Óleo Essencial da Folha", Jurnal Kimia Sains dan Aplikasi, vol. 22, no 6, pp. 269-274, Nov. 2019 CRUZ, E.N.S.; PEIXOTO, L.S.; COSTA, J.S.; MOURÃO, R.H.V.; NASCIMENTO, W.M.O.; MAIA, J.G.S.; SETZER, W.N.; SILVA, J.K.; FIGUEIREDO, P.L.B. Seasonal variability of a caryophyllene chemotype essential oil of Eugenia patrisiiVahloccurring in the Brazilian Amazon. Molecules, v.27, n.8, pp 2417, 2022. DEEPIKA, S.; SELVARAJ, C.I.; ROOPAN, S.M. Screening bioactivities of Caesalpinia pulcherrima L. swartz and cytotoxicity of extract synthesized silver nanoparticles on HCT116 cell line. Materials Science & Engineering C, v.106, pp 110279, 2020. DEET: https://pubchem.ncbi.nlm.nih.gov/compound/DEET-d10. Acessoem 01 de junho de 2022. DHAKED, P.S.; KSHIRSAGAR, S.N.; SAKARAR, D.M. Antimicrobial activity of ethanolic and aqueous extract ofCaesalpinia pulcherrimaflowers.International. Journal of Pharmaceutical Sciences and Research, v.2,n.10, pp 2643-2646, 2011. DRUMMOND, M.R.; LANIA, B.G.;DINIZ, P.P.V.P.; GILIOLI, R.; DEMOLIN, D.M.R.; SCORPIO, D.G.;BREITSCHWERDT, E.B.; FERREIRA VELHO, P.E.N. Improvement of Bartonella henselae DNA detection in cat blood samples by combining molecular and culture methods. Journal of Clinical Microbiology, v.56,n.5, pp e01732- 17, 2018. DRYDEN, M.W. Flea and tick control in the 21st century: challenges and opportunities. VeterinaryDermatology, v.20, n.5-6, pp 435–440, 2009. DUARTE, M.C.T. Atividade antimicrobiana de plantas medicinais e aromáticas utilizadas no Brasil. MultiCiência, v.7, pp 1-16, 2006. EL-KAREEM, M.S.M.A.; RABBIH, M.A.; ELANSARY, H.O.; AL-MANA, F.A. Mass spectral fragmentation of Pelargonium graveolens essential oil using GC-MS semi-empirical calculations and biological potential. Processes, v.8, n.128, pp 1-19, 2020. ELLSE, L.& WALL, R. The use of essential oils in veterinary ectoparasite control: A review. Medical and Veterinary Entomology, v.28, n.3, pp 233–243, 2014. 65 ELLMAN, G.L.; COURTEY, K.D.; ANDRES JR, V.; FEATHERSTONE, R.M.A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, v.7, n.2, pp 88–90, 1961. ERHARUYI, O.; ADHIKARI, A.; FALODUN, A.; JABEEN, A.; IMAD, R.; AMMAD, M.; CHOUDHARY, M. I.; GÖREN, N. Cytotoxic, anti-inflammatory, and leishmanicidal activities of diterpenes isolated from the roots of Caesalpinia pulcherrima.Planta Medica, v.83, pp 104-110, 2017. ERHARUYI, O.; IMIEJE, V. O.; OSEGHALE, I. O.; UBHENIN, A. E.; FALODUN, A. & CHOUDHARY, M. I. Identification of Compounds and Insecticidal Activity of Barbadian Pride Root (Caesalpinia Pulcherrima check for this species in other resources L Journal of Applied Sciences and Environmental Management, Vol. 21, No. 2, pp. 281- 287, 2017. ESCCAP. Control of Ectoparasites in Dogs and Cats. 4 ed., 2015. FACHINI-QUEIROZ, F.C.; KUMMER, R.; ESTEVÃO-SILVA, C.F.; CARVALHO, M.D.B.; CUNHA, J.M.; GRESPAN, R.; BERSANI-AMADO, C.A.; CUMAN, R.K.N. Effects of thymol and carvacrol, constituents of Thymus vulgaris L. essential oil, on the inflammatory response. Evidence-Based Complementary and Alternative Medicine, v.2012, pp 657026, 2012. FALCO, E.; MANCINI, E.; ROSCIGNO, G.; MIGNOLA, E.; TAGLIALATELA- SCAFATI, O.; SENATORE, F. Chemical composition and biological activity of essential oils of Origanum vulgare L. subsp. Vulgare L. under different growth conditions. Molecules, v.18, pp 14948-14960, 2013. FORIM, M.R., MATOS, A.P., da SILVA, M.F.G.F., CASS, Q.B., VIEIRA, P.C., & FERNANDES, J.B. (2010b). Uso de CLAE no controle de qualidade em produtos comerciais de nim: reprodutibilidade da ação inseticida. Química Nova, 33, 5, pp. 1082- 1087 2012. FRADIN, M.S.& DAY, J.F. Comparative efficacy of insect repellents against mosquito bites. The New England Journal of Medicine, v.347,n.1, pp 13-18, 2002. GALOVIČOVÁ, L.; BOROTOVÁ, P.; VALKOVÁ, V.; VUKOVIC, N.L.; VUKIC, M.; ŠTEFÁNIKOVÁ, J.; ĎÚRANOVÁ, H.; KOWALCZEWSKI, P.L.; ČMIKOVÁ, N.; KAČANIOVÁ, M. Thymus vulgaris essential oil and its biological activity. Plants, v.10, n.9, 1959, 2021. GAO, S.; LIU, G.; LI, J.; CHEN, J.; LI, L.; LI, Z.; ZHANG, X.; ZHANG, S.; THOME, R.F.; ZHANG, S. Antimicrobial activity of lemongrass essential oil (Cymbopogon flexuosus) and its active component citral against dual-species biofilms of Staphylococcus aureus and Candida species. Frontiers in Cellular and Infection Microbiology, 10:603858,2020. doi: 10.3389/fcimb.2020.603858. GOVIL, J.N. & TIWARI, L. Recent progress in medicinal plants: phytoconstituents and biochemical processes. Vol.35. Houston: Studium Press LLC LTD., 2013. 66 GOVINDARAJAN, M. et al. Ovicidal and repellent activities of botanical extracts against Culex quinquefasciatus, Aedes aegypti and Anopheles stephensi (Diptera: Culicidae). Asian Pacific Journal of Tropical Biomedicine. 1: 43-48, 2011. GOVINDARAJAN, M. RAJAMOHAN, S., RAJESWARY, M., & YOGALAKSHMI, K. Chemical composition and larvicidal activity of essential oil from Ocimum basilicum (L.) against Culex tritaeniorhynchus, Aedes albopictus and Anopheles subpictus (Diptera: Culicidae). Experimental parasitology. 134. 10.1016/j.exppara. 2013. GUPTA, R.C.; DOSS, R.B.; SRIVASTAVA, A.; LALL, R.; SINHA, A. Nutraceticals for control of ticks, fleas and other ectoparasites. Springer Nature Switzerland, pp 625- 632, 2019. HALOS, L.; BEUGNET, F.; CARDOSO, L.; FARKAS, R.; FRANC, M.; GUILLOT, J.; PFSISTER, K.; WALL, R. Flea control failure? Myths and realities. Trends in Parasitology, v.30, n.5, pp 228–233, 2014. HASSIOTIS, C.N.; NTANA, F.; LAZARI, D.M.; POULIOS, S.; VLACHONASIOS, K.E. Environmental and developmental factors affect essential oil production and quality of Lavandula angustifolia during flowering period. Industrial Crops and Products, v.62, pp 359-366, 2014. HAWKINS, N.J.; BASS, C.; DIXON, A.; NEVE, P. The evolutionary origins of pesticide resistance. Biological Reviews, v.94, pp 135-155, 2019. HYLDGAARD, M.; MYGIND, T.; MEYER, R.L. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. Frontiers in Microbiology, v.3, n.12, 2012, doi: 10.3389/fmicb.2012.00012 IGE, P.P.; AGRAWAL, K.; PATIL, U. Enhanced in vitro dissolution of iloperidone using Caesalpinia pulcherrima mucoadhesive microspheres. ScienceDirect, v.4, pp 26- 32, 2015. KABERA, J.; GASOGO, A.; UWAMARIYA, A.; UGIRINSHUTI, V.; NYETERA, P. Insecticidal effects of essential oils of Pelargonium graveolens and Cymbopogon citratus on Sitophilus zeamais (Motsch.). Affrican Journal of Food Sciences, v.5,n.6, pp 366–375, 2011. KHALIL, M.N.A.; FARGHAL, H.H.; FARAG, M.A. Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi- faceted Grapefruit Citrus X paradisi: A comprehensive review for maximizing its value. Critical Reviews in Food Science and Nutrition,v.62, n.4, pp 935-956,2020. KLASSEN, C.D.& WATKINS III, J.B. Fundamentosemtoxicologia de Casarett e Doull. 2a edição. Porto Alegre:AMGHEditora Ltda., 2012, 460ps. KRAKER, J.W.; FRANSSEN, M.C.R.; GROOT, A.; KÖNIG, W.A.; BOUWMEESTER, H.J. (+)-Germacrene a biosynthesis: the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory. Plant Physiology, v.117, n.4, pp 67 1381-1392, 1998. KUMAR, D.; SINGH, J.; BAGHOTIA, A.; KUMAR, S. Anticonvulsant effect of the ethanol extract ofCaesalpinia pulcherrima(L.) Sw., Fabaceae, leaves.RevistaBrasileira de Farmacognosia, v.20,n.5, pp 751-755, 2010. KUMBHARE, M.R.; SIVAKUMAR,T.; UDAVANT, P.B.; DHAKE, A.S.; SURANA, A.R. In vitro antioxidant activity, phytochemical screening, cytotoxicity and total phenolic content in extracts of Caesalpinia pulcherrima (Caesalpiniaceae) pods.Pakistan Journal of Biological Sciences, v.15,n.7, pp 325-332, 2012. LAHLOU, M. Methods to study the phytochemistry and bioactivity of essential oils. Phytotherapy Research, v. 18, n. 6, p. 435-48, 2004 LAMBERT, M.M.; CAMPOS, D.R.; BORGES, D.A.; AVELAR, B.R.; FERREIRA, T.P.; CID, Y.P.; BOYLAN. F.; SCOTT, F.B.; CHAVES, D.S.A.; COMENDOUROS, K. Activity of Syzygiumaromaticum essential oil and its main constituent eugenol in the inhibition of the development of Ctenocephalides felisfelis and the control of adults. VeterinaryParasitology, v.282, pp 109126, 2020. LARINI, L. Toxicologia dos Praguicidas. São Paulo: Editora Manole Ltda., 1999. 230ps. LARINI, L. Toxicologia. 3a edição. São Paulo: Editora Manole Ltda., 1997. 301p. LEMKE, T.L.; WILLIAMS, D.A.; ROCHE, V.F.; ZITO, S.W. FOYE’s Principles of medicinal chemistry. 6 a edição. Baltimore: Lippincott Willians& Wilkins, 2008. 1377ps. LIMA, E.A.S.; CONCEIÇÃO, C.L.; GIJISEN, I.S.; CHAVES, J.K.O.; CAMPOS, D.R.; FERREIRA, T.P.; ALVES, M.C.C.; COMENDOUROS, K. AvaliaçãodopotencialinseticidadoóleoessencialdeCitrusparadisinocontroledosestágiosi maturoseadultosdeCtenocephalidesfelis. ArchivesofVeterinary Science, v.25, n.5, pp107,ISSN 2317-6822, 2020. doi:http://dx.doi.org/10.5380/avs.v15i5.77064. Disponível em: https://revistas.ufpr.br/veterinary/article/view/77064. Acesso em: 16maio 2022. LINARDI, P.M.& SANTOS, J.L.C. Ctenocephalidesfelisfelis vs. Ctenocephalides canis (Siphonaptera: Pulicidae): some issues in correctlyidentifythesespecies. Revista Brasileira de Parasitologia Veterinária, v.21,n.4, pp 345-354, 2012. LINARDI, P.M.& GUIMARÃES, L.R. Sifonápteros do Brasil. São Paulo: Editora Museu de Zoologia USP/FAPESP, 2000. 291p. LIMONGI, J.E.; SILVA, J.J.; PAULA, M.B.C; MENDES, J. Aspectos epidemiológicos das infestações por sifonápteros na área urbana do município de Uberlândia, Minas Gerais, 2007-2010. Epidemiologia e Serviços de Saúde, v.22,n.2, pp 285-294, 2013. LUÍS, A.; DUARTE, A.; GOMINHO, J.; DOMINGUES, F.; DUARTE, A.P. Chemical composition, antioxidant, antibacterialandanti quorumsensingactivitiesofEucalyptusglobulusandEucalyptusradiataessentialoils. 68 Industrial Crops and Products, v.79, pp 274-282, 2016. MAGURANYI, S.K.; WEBB, C.E.; MANSFIELD, S.; RUSSELL, R.C. Are commercially available essential oils from Australian native plants repellent to mosquitoes? Journal of the American Mosquito Control Association, v.25, n.3, pp 292- 300, 2009. MAIA, M.F.& MOORE, S.J. Plant-based insect repellents: a review of their efficacy, development and testing. Malaria Journal, v.10, n.511, pp 1-14, 2011. MANIKKAM, M.; TRACEY, R.; GUERRERO-BOSAGNA, C.; SKINNER, M.K. Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations. Reproductive Toxicology, v.34, n.4, pp 708-719, 2012. MARCUS, E.M. & JACOBSON, S. Integrated neuroscience: a clinical problem solving approach. New York: Springer Science Business Media, 2003. MONTANARI, R.M.; BARBOSA, L.C. A.; DEMUNER, A.J.; SILVA, C.J.; CARVALHO, L.S.; ANDRADE, N.J. Chemical composition and antibacterial activity of essential oils from verbenaceae species: alternative sources of (E)-caryophyllene and germacrene-D Quimica Nova 34(9): pp 1550-1555, 2011. MUNDO ECOLOGIA: Pulga de gato. Disponível em: https://www.mundoecologia.com.br/ animais/pulga-do-gato-caracteristicas-nome- cientifico-e-fotos/. Acesso em 09 de novembro de 2021. NAJIBULLAH, S.N.M.; AHAMAD, J.; ALDAHISH, A.A.; SULTANA, S.; SULTANA, S. Chemical characterization and -glucosidase inhibitory activity of essential oil of Lavandula angustifolia flowers. Journal of Essential Oil-Bearing Plants, v.24, n.3, pp 431-438, 2021. NAQQASH, M.N.; GÖKÇE, A.; BAKHSH, A.; SALIM, M. Insecticide resistance and its molecular basis in urban insect pests. ParasitologyResearch, v.115, pp 1363-1373, 2016. NASCIMENTO, K.F.; MOREIRA, F.M.F.; SANTOS, J.A.; KASSUYA, C.A.L.; CRODA, J.H.R.; CARDOSO, C.A.L.; VIEIRA, M.C.; RUIZ, A.L.T.G.; FOGLIO, M.A.; CARVALHO, J.E.; FORMAGIO, A.S.N.Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil ofPsidium guineenseSw. and spathulenol. Journal of Ethnopharmacology, v.210, pp 351–358, 2018. NJOKU, I., OLAYNKA, A. & FAMILONI, O. The Effect of Drying Methods on the Chemical Composition of the Essential Oil of Caesalpinia Pulcherrima Growing in Lagos, Nigeria. v.4, pp 1-3 (2016). OCHOA, R.; RODRIGUEZ, C. A.; ZULUAGA, A. F. Perspectives for the structure based design of acetylcholinesterase reactivators. Journal of Molecular Graphics and Modelling, v. 68, p. 176–183, 2016. 69 OKUNOWO, W.O.; OYEDEJI, O.; AFOLABI, L.O.; MATANMI, E. Essential oil of grape fruit (Citrus paradisi) peels and its antimicrobial activities. American Journalof Plant Sciences, v.4, pp 1-9, 2013. OLIVEIRA, A.C.; MACHADO, J.A.C; ANTÔNIO, N.S.; NEVES, M.F. Ctenocephalides Canis Canis e CtenocephalidesFelis: Revisão de Literatura. Revista Cientifica Eletrônica de Medicina Veterinária, v.06, n.11, pp I–V, 2008. OPYDIKE, D. L. J.; Food and Cosmetics Toxicol. 1973,11,1059 ORAPUN Y., CHATCHANOK K., CHANITA P., SUPINYA T., SUCHADA C. Pulcherrins D-R, potenciais diterpenóides anti-inflamatórios das raízes de Caesalpinia pulcherrima. Tetraedro 2011, 67 (36), 6838-6846. https://doi.org/10.1016/j.tet.2011.06.087 PAWAR C.R, MUTHA R.E, LANDGE A.D, JADHAY R.B, and SURANA S.J. Antioxidant and cytotoxic activities of Caesalpinia pulcherrima wood. Indian Journal of Biochemistry and Biophysics.; v 46: pp, 198-200, 2009. PETRAKIS, P.V.; ROUSSIS, V.; PAPADIMITRIOU, D.; VAGIAS, C.; TSITSIMPIKOU, C. The effect of terpenoid extracts from 15 pine species on the feeding behavioural sequence of the late instars of the pine processionary caterpillar Thaumetopoeapityocampa. Behavioural Processes, v.69, n.3, pp 303-322, 2005. PRIETO, J.A.; PATINO, O.J.; DELGADO, W.A.; MORENO, J.P.; CUCA, L.E. Chemical Composition, Insecticidal, and Antifungal Activities of Fruit Essential Oils of Three Colombian Zanthoxylum Species. Chilean Journal of Agricultural Research, v.71, n.1, pp 73-82,2011. QUAN M, LIU Q. Z, LIU Z. L. Identification of Insecticidal Constituents of the Essential Oil of Aerial Parts Stachys riederi var. japonica. molecules. May 17,;23(5):1200, 2018. doi: 10.3390/molecules23051200. PMID: 29772795; PMCID: PMC6099633. PULIPATI, S.; PALLAVI, G.; SUJAN, B.; BABU, K.A.; BABU, P.S. Evaluation of antibacterial activity of fresh and dry flower extracts of Caesalpina pulcherrima L. International Journal of Biological & Pharmaceutical Research, v.3,n.3, pp 360-365, 2012. RADULOVIĆ, N.; LAZAREVIĆ, J.; RISTIĆ, N.; PALIĆ, R. Chemotaxonomic significance of the volatiles in the genus Stachys (Lamiaceae): essential oil composition of four Balkan Stachys species. Biochemical Systematics and Ecology, v.35, n.4, pp 196-208, 2007. RHEE, I.K.; MEENT, M.V.; INGKANINAN, K.; VERPOORTE, R. Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. Journal of Chromatography A, v.915, n.1–2, pp 217–223, 2001. 70 RUST, M. Advances in the control of (cat flea) on cats and dogs. Trends in Parasitology, v.21, n.5, pp 232–236, 2005. SAID-AL AHL, H.A.H.; HIKAL, W.M.; TKACHENKO, K.G. Essential Oils with Potential as Insecticidal Agents: A Review. International Journal of Environmental Planning and Management, v.3, n.4, pp 23–33, 2017. SATIAL, P.; SHRESTHA, S.; SETZER, W.N. Composition and Bioactivities of an (E)- β-Farnesene Chemotype of Chamomile (Matricaria chamomilla) Essential Oil from Nepal.Natural Product Communications, v.10, n.8, pp 1453-1457, 2015. SELVI, R.S.; GOPALAKRICHANAN, S.; RAMAJAYAM, M.; SOMAN, R. Evaluation of mucilage of Caesalpinia pulcherrima as binder for tablets. International Journal of ChemTech Research, v.2, n.1, pp 436-442, 2010. SILVA, S. M. S. DA. Intoxicações por inibidores da acetilcolinesterase: etiologia, diagnóstico e tratamento. 47 f. Artigo de revisão (Mestrado integrado em Medicina) - Faculdade De Medicina Da Universidade De Coimbra, Coimbra, 2015. SILVA, L.E.; GONÇALVES, M.V.S.; AMARAL, W.; QUADROS, D.A.; REIS, R.A.; AMARAL, L.D.P.; HUERGO, L.F.; GARCIA, B. Chemical composition and antibacterial activity of Cymbopogon citratus and Cymbopogon flexuosus essential oils. Ciência e Natura, v.40, e2, 2018. SILVA, F.D.B.; SALES, M.A.G.; SÁ, O.R.M.; DEUS, M.S.M.; SOUZA, J.M.C.; PERON, A.P.; FERREIRA, P.M.P. Potencialcitotóxico, genotóxico e citoprotetor de extratosaquosos de CaesalpiniapyramidalisTul., CaesalpiniaferreaMart. e CaesalpiniapulcherrimaSw. Revista Brasileira de Biociências, v.13, n.2, pp 101-109, 2015. SIMÕES, M. M, LEITE, M.F.M.S, MEDEIROS, M.A.C, Atividade antineoplásica do germacreno-d: um teste in sílico. Anais I CONIMAS e III CONIDIS... Campina Grande: Realize Editora, 2019. Disponível em: <https://www.editorarealize.com.br/artigo/visualizar/63235>. Acesso em: 25/05/2022 12:54 SIMÕES, C.M.O.; SCHENKEL, E.P.; MELLO, J.C.P.; MENTZ, L.A.; PETROVICK, P.R. Farmacognosia: do produto natural ao medicamento. Porto Alegre: EditoraArtMed, 2017. 486ps. SOUTAR, O.; COHEN, F.; WALL, R. Essential oils as tick repellents on clothing. Experimental and Applied Acarology, v.79, pp 209-219, 2019. SOUZA, G.A.; SILVA, S.J.; CISTIA, C.N.D.; PITASSE-SANTOS, P.; PIRES, L.O.; PASSOS, Y.M.; CORDEIRO, Y.; CARDOSO, C.M.; CASTRO, R.N.; SANT’ANNA, C.M.R.; KÜMMERLE, A.E. Discovery of novel dual-active 3-(4- (dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potentandselectiveacetylcholinesteraseinhibitorandantioxidant. Journal of Enzyme Inhibition and Medicinal Chemistry, v.34, n.1, pp 631-637, 2019. 71 SOUZA, R.A.; ALMEIDA, R.M.; SILVA, C.C.; MACÊDO, A.A.M. Propriedades elétricas dos filmes de polissacarídeos. The Journal of Engineering and Exact Sciences, v.3, n.8, pp 1243-1249, 2017. STEFANI, G. P; PASTORINO, A. C; CASTRO, A. P. B. M.; FOMIN, A. B. F.; JACOB, C. M. A. Repelentes de insetos: recomendações para uso em crianças. Rev Paul Pediatr;27(1):81-9, 2009 SURYAWANSHI, S.R.; THAKARE, N.P.; MORE, D.P.; THOMBRE, N.A. Bioavailability enhancement of ondansetron after nasal administration of Caesalpinia pulcherrima-based microspheres. Drug Delivery, v.22, n.7, pp 894-902, 2015. SUTTON, G.P. & BURROWS, M. Biomechanics of jumping in the flea. Journal of Experimental Biology, v.214, n.5, pp 836–847, 2011. TAN, N., SANTANA, D., SEM, B., TAN, E., ALTAN, H.B., DEMIRCI, B.; UZUN, M. Antimycobacterial and antifungal activities of selected four Salvia species. Records of Natural Products, v.10, n.5, pp 593–603, 2016. TAYLOR, M. A. Recent developments in ectoparasiticides. The Veterinary Journal, v. 161, n. 3, p. 253 – 268, 2001 TEIXEIRA, B.; MARQUES, A.; RAMOS, C.; SERRANO, C.; MATOS, O.; NENG, N.R.; NOGUEIRA, J.M.F.; SARAIVA, J.A.; NUNES, M.L. Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. Journal of the Science ofFood and Agriculture, v.93, n.11, pp 2707-2714, 2013. TENÓRIO, T.M.A.; MORAES, M.M.; CAMARA, C.A.G. Composição química e atividade acaricida dos óleos essenciais de duas espécies da família Myrtaceae. Caderno Verde de Agroecologia e Desenvolvimento Sustentável, v.9, n.5, b-90, 2019. THE STATIONERY OFFICE. British Pharmacopoeia, 10a edition, vol.1-5. London: Medicines and Healthcare Products Regulatory Agency (MHRA), 2020. THOMBRE, N.A.& GIDE, P.S. Floating-bioadhesivegastroretentiveCaesalpinia pulcherrima-based beads of amoxicillin trihydrate for Helicobacter pylori eradication. Drug Delivery, v.23, n.2, pp 405-419, 2016. TREVISAN, M.T.S.; MACEDO, F.V.V.; MEENT, M.V.; RHEE, I.K.; VEPOORTE, R. Screening for acetylcholinesterase inhibitors from plants to treat Alzheimer’s disease. Química Nova, v.26, n.3, pp 301–304, 2003. TRIPATHI, A. K.; MISHRA, S. Plant monoterpenoids (prospective pesticides). In: ECOFRIENDLY pest management for food security. Amsterdam: Academic Press, 2. p. 507-524, 2016. 72 TOLEDO, L.G.; RAMOS, M.A.S.; SPÓSITO, L.; CASTILHO, E.M.; PAVAN, F.R.; LOPES, E.O.; ZOCOLO, G.J.; SILVA, F.A.N.; SOARES, T.H.; SANTOS, A.G.; BAUAB, T.M.; ALMEIDA, M.T.G. Essential oil of Cymbopo gonnardus(L.) rendle: a strategytocombatfungalinfectionscausedby Candidaspecies. International Journal of Molecular Sciences, v.17, n.8, pp 1252, 2016. doi:10.3390/ijms17081252 TRONGTOKIT, Y.; RONGSRIYAM, Y.; KOMALAMISRA, N.; APIWATHNASORN, C. Comparative repellency of 38 essential oils against mosquito bites. Phytotherapy Research, v.19, n.4, pp 303-309, 2005. USMAN, L.A., ZUBAIR, M.F., OLAWORE, N.O., ASHAMU, M., ISMAELL, R.O. and OLADOSU, I.A. (2012). Chemical constituents of leaf essential oils of two varieties of Caesalpinia pulcherrima Linn growing in north central Nigeria. Elixir. Org. Chem. 44: 7085-7087. VANDERAH, T.W. Nolte – fundamentos de neuroanatomia. 2a edição. Rio de Janeiro: Elsevier Editora, 2019. VAZIRIAN, M.; MOHAMMADI, M.; FARZAEI, M.H.; AMIN, G.; AMANZADEH, Y. Chemical composition and antioxidant activity of Origanum vulgare subsp. Vulgare essential oil from Iran. Research Journal of Pharmacognosy, v.2, n.1, pp 41-46, 2015. VERÍSSIMO, C.J. Resistência e controle do carrapato-do-boi. Nova Odessa: Instituto de Zootecnia, 2015. 135p. YANG, X.; WEI, X.; YANG, J.; DU, T.; YIN, C.; FU, B.; HUANG, M.; LIANG, J.; GONG, P.; LIU, S.; XIE, W.; GUO, Z.; WANG, S.; WU, Q.; NAUEN, R.; ZHOU, X.; BASS, C.; ZHANG, Y. Epitranscriptomic regulation of insecticide resistance. Science Advances, v.7, pp eabe5903, 2021 WEZEL, A. et al. Agroecological practices for sustainable agriculture. A review. Agronomy for Sustainable Development, v. 34, n. 1, p. 1–20, jan. 2014. ZHANG, J-P.; QIN, Y-G.; DONG, Y-W.; SONG, D-L.; DUAN, H-X.; YANG, X-L. Synthesis and biological activities of (E)-β-farnesene analogues containing 1,2,3- thiadiazole. Chinese Chemical Letters, v.28, n.2, pp 372-376, 2017. ZIELINSKI, E. Indispensable essential oils starter guide. Natural Living Family, 2021. 150ps. ZORZENON, F.J.& JUNIOR, J.J. Manual ilustrado de pragas urbanas e outros animais sinantrópicos. CIDADE?:Instituto Biológico, 151p, 2006. | pt_BR |
| dc.subject.cnpq | Química | pt_BR |
| Appears in Collections: | Mestrado em Química | |
Se for cadastrado no RIMA, poderá receber informações por email.
Se ainda não tem uma conta, cadastre-se aqui!
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2022 - Wladymir Mendes Carvalho de Castro.Pdf | 1.62 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.