logo RIMA
logo UFRRJ

  1. Repositório de Múltiplos Acervos da UFRRJ
  2. Teses e Dissertações
  3. Programa de Pós-Graduação em Ciências Veterinárias
  4. Doutorado em Ciências Veterinárias
Please use this identifier to cite or link to this item: https://rima.ufrrj.br/jspui/handle/20.500.14407/9686
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRoier, Erica Cristina Rocha
dc.date.accessioned2023-12-21T18:42:38Z-
dc.date.available2023-12-21T18:42:38Z-
dc.date.issued2011-02-28
dc.identifier.citationROIER, Erica Cristina Rocha. Neorickettsia risticii: aspectos clínicos, hematológicos, sorológicos e moleculares em equinos na microrregião de Itaguaí, Rio de Janeiro. 2011. 43 f. Tese (Mestrado em Ciências Veterinárias) - Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, 2011.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/9686-
dc.description.abstractO presente estudo teve por objetivo avaliar a prevalência de anticorpos contra Neorickettsia risticii em equinos na microrregião de Itaguaí-RJ, demonstrar os possíveis fatores associados e identificar o agente através de técnicas moleculares. O estudo foi conduzido nos municípios de Seropédica, Itaguaí e Mangaratiba, estado do Rio de Janeiro. As 350 amostras de sangue foram obtidas por conveniência, das propriedades de criação de equinos pertencentes à região. O teste sorológico foi realizado através da Reação de Imunofluorescência Indireta (RIFI) para N. risticii, sendo consideradas positivas amostras com título 1:50. Para avaliação dos fatores de risco associados à presença de anticorpos de N. risticii, aplicou-se um questionário epidemiológico com os proprietários e/ou responsáveis dos animais, destacando características da propriedade e manejo dos animais. Realizou-se hemograma e avaliação clínica de todos os animais. As análises moleculares através da técnica de Real Time PCR foram realizadas a partir de capa leucocitária. A prevalência de anticorpos anti-N. risticii em equinos da microrregião de Itaguaí foi de 26,3% (92/350) pela RIFI. As frequências de anticorpos IgG anti-N. risticii foram 52,2% (48/92) para titulações de 1:50, zero para titulações de 1:100, 13% (12/92) para títulos de 1:200, 28,3% (26/92) para títulos de 1:400 e 6,5% (6/92) para títulos de 1:800. A idade e o nível de qualidade das propriedades apresentaram associação (p<0,05) com a soropositividade dos equinos para N. risticii. Não foi detectado o DNA de N. risticii nas amostras do presente estudo. Também não foram evidenciadas alterações significativas na avaliação clinica dos animais, em relação à soropositividade para o agente. Apesar de haver associação (p<0,05) entre a soropositividade dos animais e alterações no leucograma dos animais negativos, estas alterações não estiveram fora dos limites de referência para a espécie animal avaliada. A existência de equinos soropositivos para N. risticii indica a circulação desse agente na microrregião de Itaguaípor
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopor
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectNeorickettsia risticiieng
dc.subjectEhrlichiosis Monocytic Equineeng
dc.subjectHorseseng
dc.subjectEpidemiology.eng
dc.subjectErliquiose Monocítica Equinapor
dc.subjectEquinospor
dc.subjectEpidemiologia.por
dc.titleNeorickettsia risticii: aspectos clínicos, hematológicos, sorológicos e moleculares em equinos na microrregião de Itaguaí, Rio de Janeiropor
dc.title.alternativeNeorickettsia risticii: clinical, hematological, serological and molecular techniques in horses in the microregion of Itaguai, Rio de Janeiroeng
dc.typeTesepor
dc.description.abstractOtherThis study aimed to evaluate the prevalence of antibodies against Neorickettsia risticii in horses in the microregion of Itaguaí RJ, show possible associated factors and identify the agent by molecular techniques. The study was conducted in the districts of Seropédica, Itaguaí and Mangaratiba, Rio de Janeiro. The 350 blood samples were obtained by convenience from horse properties belonging to the region. Serologic testing was performed by Immunofluorescence Assay (IFAI) for N. risticii, being considered positive samples titer 1:50. To evaluate risk factors associated with the presence of antibodies to N. risticii an epidemiological questionnaire was applied to the owners or guardians of animals, which aimed especially farm characteristics and management of animals. Hematological and clinical evaluation was performed for all animals. Molecular analysis by a Real Time PCR was performed from leukocyte cover. The prevalence of antibodies anti-N.risticii in horses of the region of Itaguaí was 26.3% (92/350). The frequencies of IgG anti-N.rristicii were 52.2% (48/92) for titers of 1:50, zero for titers of 1:100, 13% (12/92) for titles of 1:200, 28.3% (26/92) for evidence of 1:400 and 6.5% (6 / 92) for titles of 1:800. The age and quality level of the properties were associated (p <0.05) with horses seropositivity for N. risticii. DNA from N. risticii was not detectable in samples of this study. Also no significant changes in the clinical evaluation of animals was found in relation to seropositivity for the agent. Despite showing association (p <0.05) between the seropositivity of the animals and changes in white blood cell of negative animals, these changes were not outside reference limits for the species evaluated. The existence of horses seropositive for N. risticii indicates the presence of this agent in the microregion of Itaguaí.eng
dc.contributor.advisor1Massard, Carlos Luiz
dc.contributor.advisor1ID257.781.297-34por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/7743112049924654por
dc.contributor.advisor-co1Baldani, Cristiane Divan
dc.contributor.advisor-co1ID044.128.097-81por
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/6210245465538447por
dc.contributor.referee1Leite, Romário Cerqueira
dc.contributor.referee2Linhares, Guido Fontgalland Coelho
dc.contributor.referee3Barreira, Jairo Dias
dc.contributor.referee4Grisi, Laerte
dc.creator.ID023.688.377-10por
dc.creator.Latteshttp://lattes.cnpq.br/3538932429235543por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Ciências Veterináriaspor
dc.relation.referencesATWILL, E.R.; MOHAMMED, H.O.; LOPEZ, J.W.; McCULLOCH, C.E.; DUBOVI, E.J.Cross-sectional evaluation of environmental, host and management factors associated with risk of seropositivity to Ehrlichia risticii in horses of New York state. American Journal Veterinary Research, v.57, p. 278-285, 1996. ATWILL, E.R.; MOHAMMED, H.O.; DUBOVI, E.; LOPES, J. Retrospective evaluation of factors associated with the risk of seropositivity to Ehrlichia risticii in horses in New York state. American Journal Veterinary Research, v.53, p. 1931-1934, 1992. ATWILL, E.R.; MOHAMMED, H.O.; RUA-DOMENECH, R. Geographical variation of seropositivity to Ehrlichia risticii (Equine monocytic ehrlichiosis) of horses in New York State. Equine Veterinary Journal, v.26, n.2, p.143-147, 1994. AYRES, M.; AYRES JR., M.; AYRES, D.; SANTOS, A.A.S. BioEstat 5.0 – Aplicações Estatísticas nas Áreas das Ciências Biológicas e Médicas. Sociedade Civil Mamirauá, Tefé, 2007. 380 p. BARLOUGH, J.E.; REUBEL, G.H.; MADIGAN, J.E.; VREDEVOE, L.K.; MILLER, P.E.; RIKIHISA, Y. Detection of Ehrlichia risticii, the Agent of Potomac Horse Fever, in Freshwater Stream Snails (Pleuroceridae: Juga spp) from Northern California. Applied and Environmental Microbiology, v.64, p.2888-2893, 1998. BISWAS, B.; VEMULAPALLI, R.; DUTTA, S. Detection of Ehrlichia risticii from feces of infected horses by immunomagnetic separation and PCR. Journal of Clinical Microbiology, v.32, n. 9, p. 2147-2151, 1994. BOGDAN, A.V. Tropical pasture and fodder plants. New York, Longman, 1977. 475p. BREIDER, M.A.; HENTON, J.E. Equine monocytic ehrlichiosis (Potomac Horse Fever). Equine Pratice, v.9, p.20-24, 1987. BURG, J. G.; ROBERTS, A. W.; WILLIAMS, N. M.; POWELL, D. C.; KNAPP, F. W. Attempted Transmission of Ehrlichia risticii (Rickettsiaceae) with Stomoxys calcitrans (Diptera: Muscidae). Journal of Medical Entomology, v.5, n. 27, 1990. CASSAMAGNAGHI, A.; CASSAMAGNAGHI, A. Anemia infecciosa. Su reconocimiento em los equinos Del Uruguay, Veterinary Uruguay, v.4, p. 772-807, 1948. CHAE, J-S.; KIM, M-S.; MADIGAN, J. Detection of Neorickettsia (Ehrlichia) risticii in tissues of mice experimentally infected with cercariae of trematodes by in situ hybridization. Veterinary Microbiology, v.88 p.233–243, 2002. CHAE, J.S.; PUSTERLA, N.; JOHNSON, E.; DEROCK, E.; LAWER, S.P; MADIGAN, J.E. Infection of aquatic insects with trematodes metacercariae carrying Ehrlichia risticii, the causative Potomac horse fever. Journal of Medical Entomology, v. 37, p. 619-625, 2000. COIMBRA, H.S.; FERNANDES, C.; SOARES, M.P. MEIRELES, M.C.A.; RADAMES, R.; SCHUCH, L.F.D. Erliquiose monocítica equina no Rio Grande do Sul: Aspectos clínicos, 30 anátomo-patológicos e epidemiológicos. Pesquisa Veterinária Brasileira, v. 26, p. 97-101, 2006. COIMBRA, H.S.; SCHUCH, L.F.D.; VEITENHEIMER-MENDES, I.L.; MEIRELES, M.C.A. Neorickettsia (Ehrlichia) risticii no sul do Brasil: Heleobia spp. (Mollusca: Hydrobilidae) e Parapleurolophocecous cercariae (Trematoda: Digenea) como possíveis vetores. Arquivos do Instituto Biológico, v.72, n.3, p.325-329, 2005. COIMBRA, H.S. Erliquiose Monocítica Equina no Rio Grande do Sul: aspectos clínicos, anatomo-patológicos e epidemiológicos. 2003. Dissertação (Mestrado em Ciências) – Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas, 2003. COIMBRA, H.S.; SCHUCH, L.F.; RIET-CORREA, F.; CURCIO, B.R.; RAFFI, M.B.; DELLAGOSTIN, O.; MELLO, D.F.M.; HAAG, R. Diarréia em equinos causada por Ehrlichia risticii no Sul do Brasil. Anais XIV CONGRESSO ESTADUAL DE MEDICINA VETERINÁRIA, II CONGRESSO DE MEDICINA VETERINÁRIA DO CONE SUL, Gramado, RS, v.1, p.200. 1999. COLES, E.H. Patologia Clínica Veterinária. 3ª ed., Manole, São Paulo, 1986, 566p. CRAWFORD, T.B.; DILBECK, P. A brief survey of potomac horse fever. Veterinary Review, v.8, n.1, p.75, 1988. DAWSON, J.E.; HOLLAND, C.J.; RISTIC, M. Susceptibility of cats to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis (Potomac Horse Fever). American Journal of Veterinary Research, v.49, p. 1497, 1988. DAWSON, J.E; RISTIC, M.; HOLLAND, C.J: Isolation of Ehrlichia risticii, the causative agent of Potomac horse fever, from the fetus of an experimentally infected mare, Veterinary Record, v.121, 232, 1987. DUMLER, J.S.; BARBET, A.F.; BEKKER, C.P.J.; DASCH, G.A.; PALMER, G.H.; RAY, S.C.; RIKIHISA, Y.; RURANGIRWA, F.R. Reorganization of genera in the families Rickettsiaceace and Anaplasmataceace in the order Rickettsiales; unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and BHGE agent as subjective synonyms of Ehrlichia phagocytophila. International Journal of Systematic and Evolutionary Microbiology, v.51, p.2145–2165, 2001. DUTRA, F.; SCHUCH, L.D.F., DELUCCHI, E.; CURCIO, B.R. COIMBRA, H.F. RAFFI, M.B.; DELAGOSTIN, O.; RIET-CORREA, F. Equine monocytic Ehrlichiosis (Potomac horse fever) in horses in Uruguay and southern Brazil. Journal Veterinary Diagnostic Investigation, v.13, p.433-437, 2001. DUTTA, S.K. Present status of Research on Monocytic and granulocytic Ehrlichiosis of Animals and Humans. 1. International Vet. Mic. Cong., Univ. Istanbul, Veterinary Facult Turkey, p.25-27, 1996. 31 DUTTA, S.K.; PENNEY, B.E.; MYRUP, A.C; ROBL, M.G; RICE, R.M. Disease features in horses with induced equine monocytic ehrlichiosis (Potomac Horse Fever). American Journal Veterinary Research, v.49, p.1747- 1751, 1988 DUTTA, S.K.; RICE, R.M.; HUGHES, T.D.; SAVAGE, P.K.: MYRUP, A.C. Detection of serum antibodies against Ehrlichia risticii in Potomac Horse Fever by enzyme-linked Immunosorbent assay. Veterinary Immunology and Immunopathology, v.14, p. 85-92, 1987. DUTTA, S.K.; MYRUP, A.C.; RICE, R.C.; ROBL, M.G.; HAMMOND, R.C.: Experimental reproduction of Potomac horse fever in horse fever in horses with a newly isolated Ehrlichia organism. Journal of Clinical Microbiology, v.22, p.265-269, 1985. FERRÃO, C.M.; ABOUD-DUTRA, A.E.; LOPES, R.S.; CANDEIAS, M.L.; GAZÊTA, G.S. Equine Monocytic Ehrlichiosis (EME) in Rio de Janeiro State, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v.59, n.6, 1575-1578, 2007. FLETCHER, M.G. Determination of the possible role of arthropods as vector for Potomac Horse Fever. 95p. (Tese de Doutorado), Universidade Politécnica da Virgínia, VA, 1987. GIBSON K.E.; RIKIHISA Y.; ZHANG C.; MARTIN C. Neorickettsia risticii is vertically transmitted in the trematode Acanthatrium oregonense and horizontally transmitted to bats. Environmental Microbiology. v. 7, p. 203-212. 2005. GOETZ, T.E.; HOLLAND, C.J.; DAWSON, J.E.; RISTIC, M.; SKIBBE, K.; KEEGAN, K.G.; JOHNSON, P.J.; SCHAEFFER, D.J.; BAKER, G.J. Monthly prevalence (in 1986) of antibody titers against equine monocytic ehrlichiosis in apparently healthy horses in Illinois. American Journal Veterinary Research, v.50, n.11, p. 1936-1939, 1989. GORDON, J.C.; BECH-NIELSEN, S.; KOHN, C.; FARRAR, W.; PARSONS, M.; FOSTER, W. An Epidemiological Investigation of Farms with Potomac Horse Fever (Equine Monocytic Ehrlichiosis). Acta Veterinaria Scandinavia, s. 84, p.319-322, 1988. HAHN, N.E.; FLETCHER, M.; RICE, R.M.; KOCAN, K.M.; HANSEN, J.W.; HAIR, J.A.; BARKER, R.W.; PERRY, B.D. Attempted transmission of Ehrlichia risticii, causative agent of Potomac Horse Fever, by the ticks, Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis and Amblyomma americanum. Experimental & Applied Acarology, v.8, p.41-50, 1990. HELLER, M.C.; MCCLURE, J.; PUSTERLA, N.; PUSTERLA, J.B.; STAHEL, S. Two cases of Neorickettsia (Ehrlichia) risticii infection in horses from Nova Scotia. Canadian Veterinary Journal, v.45, p.421-423, 2004. HOLLAND, C.J.; RISTIC, M.; COLE, A.I.; JOHNSON, P.; BAKER, G.; GOETZ, T. Isolation, Experimental transmission, and characterization of Causative Agent of Potomac Horse Fever. Science, v.227, p.522-524, 1985. 32 IBGE. Instituto Brasileiro de Geografia e Estatística. Indicadores de produção pecuária. 2010. Disponível em: <http://www.sidra.ibge.gov.br/bda/territorio/ufmenu.asp?z=t&o =4>. Acessado em: 15 de Jan. 2011. JENNY, A.L. National veterinary sciences laboratories (USDA) report. American Association of Equine Practitioners, v.2, p.64-66, 1984. KANTER, M.; MOTT, J.; OHASHI, N.; FRIED, B.; REED, S.; LIN, Y.C.; RIKIHISA, Y. Analysis of 16S rRNA and 51-Kilodalton Antigen gene and Transmission in Mice of Ehrlichia risticii in Virgulate Trematodes from Elimia livescens snails in Ohio. Journal of Clinical Microbiology, v.38, p.3349-3358, 2000. KIPER, M.L.; TRAUB-DARGATZ, J.L.; SALMAN, M.D.; RIKIHISA, Y. Risk factors for equine monocytic ehrlichiosis seropositivity in horses in Colorado. Preventive Veterinary Medicine, v.13, n. 4, p. 251-259, 1992. KNOWLES, R.C.; ANDERSON, C.W.; SHIPLEY, W.D.; WHITLOCK, R.H.; PERRY, B.D.; DAVISON, J.P.; Acute equine diarrhea syndrome (AEDS): a preliminary report. In: PROCEEDINGS OF THE 29TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION OF EQUINE PRACTITIONERS, Lexington, KY, p.353–357. 1983. LAPPIN, M.R.; GRIFFIN, B.; BRUNT, J.; RILEY, A.; BURNEY, D.; HAWLEY, J.; BREWER, M.M.; JENSEN, W.A. Prevalence of Bartonella species, haemoplasma species, Ehrlichia species, Anaplasma phagocytophilum, and Neorickettsia risticii DNA in the blood of cats and their fleas in the United States. Journal of Feline Medicine and Surgery, v.8, p. 85-90, 2006. LONG, M.T. Equine Monocytic Ehrlichiosis. ROBINSON, N.E. In: Current Therapy in Equine Medicine, ed. Saunders, 5 ed., St. Loius, Missouri, p.74-77, 2003. MADIGAN, J.E.; PUSTERLA, N.; JOHNSON, E.; CHAE, J.S.; PUSTERLA, J. B.; DEROCK, E.; LAWLER, S.P. Transmission of Ehrlichia risticii, the agent of Potomac horse fever, using naturally infected aquatic insects and helminth vectors: preliminary report. Equine Veterinary Journal, v. 32, p.275–279, 2000. MADIGAN, J.E.; RIKIHISA, Y.; PALMER, J.E.; DeROCK, E.; MOTT, J. Evidence for a right rate of false-positive results with the indirect fluorescent antibody test for Ehrlichia risticii antibody in horses. Journal of American Veterinary Medical Association, v.207, n.11, p.1448-1453, 1995. MADIGAN, J.E.; DEROCK, E.; LAVAN, R.P. Clinical significance of a recent serologic survey on the incidence of Potomac horse fever in California. In: PROCEEDINGS 34th ANNUAL CONFERENCE EQUINE PRACTITIONERS, 4-7 December 1988, San Diego, CA. American Association of Equine Practitioners, p. 571-576, 1989. MESSICK, J.B, RIKIHISA, Y.: Inhibition of binding, entry or survival of Ehrlichia risticii in P388D1 cells by anti–N. risticii IgG and Fab fragments, Infection and Immunity v.62, p.3156, 1994. 33 MOTT J.; MURAMATSU Y.; SEATON E.; MARTIN C.; REED S.; RIKIHISA Y. Molecular analysis of Neorickettsia risticii in adult aquatic insects in Pennsylvania, in horses infected by ingestion of insects, and isolated in cell culture. Journal of Clinical Microbiology, v. 40, p. 690-693. 2002. MOTT J.; RIKIHISA Y.; ZHANG Y.; REED S.M.; YU C.Y. Comparison of PCR and Culture to the Indirect Fluorescent-Antibody Test for Diagnosis of Potomac Horse Fever. Journal of Clinical Microbiology, v. 35, p. 2215-2219. 1997. MULVILLE, P. Equine monocytic ehrlichiosis (Potomac horse fever): a review. Equine Veterinary Journal, v.23, p.400–404, 1991. OLCHOWY, T.W.J.; AMES, T.R; MOLITOR, T.W. Serodiagnosis of equine monocytic ehrlichiosis in selected groups of horses in Minnesota. Journal of the American Veterinary Medical Association, 15; 196 (12), p.1967-1970, 1990. OLIVER, O.E.; STÄMPFLI, H. Acute diarrhea in the adult horse: Case example and review. Veterinary Clinics Equine Practice, v.22, p. 73-84, 2006. OLSEN, W. Phylum Platyhelminthes. In: Animal parasites. Their life cycles and ecology. 3º ed. Baltimore, MD, US: University Park Press, 1974, p. 199-333. PALMER, J.E.; BENSON, C.E. Oral transmission of Ehrlichia risticii resulting in Potomac Horse Fever. Veterinary Record, v.122, p.635-639, 1988. PALMER, J.E; WHITLOCK, R.H.; BENSON, C.E. Equine ehrlichial colitis (Potomac horse fever): Recognition of the disease in Pensylvania, New Jersey, New York, Ohio, Idaho and Connecticut. Journal American Veterinary Medical Association, v. 189, p. 197-199, 1986. PARK, J.; CHOI, K.S.; DUMLER, J.S. Major surface protein 2 of Anaplasma phagocytophilum facilitates adherence to granulocytes. Infection and Immunity, v.71, p.4018–4025, 2003. PEEL, M.C.; FINLAYSON, B.L.; MCMAHON, T.A. "Updated world map of the Köppen- Geiger climate classification". Hydrology and Earth System Sciences, v.11, p.1633–1644, 2007. PERRY, B.D.; PALMER, J.E.; TROUTT, H.F.; BIRCH, J.B.; MORRIS, D.; EHRICH, M.; RIKIHISA, Y. A case-control study of Potomac horse fever. Preventive Veterinary Medicine, v.4, p.69-82, 1986. PERRY, B.D.; RIKIHISA, Y.; SAUNDERS, G. Transmission of Potomac horse fever by intradermal route. Veterinary Record, v.116, p.246–247, 1985. PRETZMAN, C.T.; RIKIHISA, Y; RALPH, D. et al: Enzyme-linked immunosorbent assay for detecting Potomac horse fever disease, Journal of Clinical Microbiology, v.25, p.31-36, 1987. 34 PRETZMAN, C.; RALPH, D.; STOTHARD, D. R.; FUERST, P. A.; RIKIHISA, Y. 16S rRNA gene sequence of Neorickettsia helminthoeca and its phylogenetic alignment with members of the genus Ehrlichia. Int J Syst Bacteriol, v. 45, p.207-211, 1995. PUSTERLA, N.; JOHNSON, E.M.; CHAE, J.S.; MADIGAN, J.E. Digenetic trematodes, Acanthatrium sp. And Lecithodendrium sp., as vectors of Neorickettsia risticii, the agent of Potomac horse fever. Journal of Helminthology, v. 77, p. 335–339, 2003. PUSTERLA, N.; MADIGAN, J.E.; CHAE, J.-S.; DEROCK, E.; JOHNSON, E.; PUSTERLA, J.B. Helminthic Transmission and Isolation of Ehrlichia risticii, the Causative Agent of Potomac Horse Fever, by Using Trematode Stages from Freshwater Stream Snails. Journal of Clinical Microbiology, v.38, p.1293-1297, 2000a. PUSTERLA, N.; JOHNSON, E.; CHAE, J.; PUSTERLA, J.B.; DeROCK, E.; MADIGAN, J.E. Infection rate of Ehrlichia risticii, the agent of Potomac Horse Fever, in freshwater stream snails (Juga yrekaensis) from northern California. Veterinary Parasitology, v.92, p. 151-156, 2000b. PUSTERLA, N.; LEUTENEGGER, C.M.; SIGRIST, B.; CHAE, J-S.; LUTZ, H.B.; MADIGAN, J.E. Detection and quantitation of Ehrlichia risticii genomic DNA in infected horses and snails by real-time PCR. Veterinary Parasitology, 90, p. 129-135, 2000c. REED, S.M; BAYLY, W.M. Medicina Interna Equina, Rio de Janeiro: Guanabara Koogan, 2000. 938p. REUBEL, G.H.; BARLOUGH, J.E.; MADIGAN, J.E. Production and characterization of Ehrlichia risticii, the agent of Potomac horse fever, from snails (Pleuroceridae Juga spp.) in aquarium culture and genetic comparison to equine strains. Journal of Clinical Microbiology, v.36, p.1501–1511, 1998. RIKIHISA, Y. Rickettsial Disease. In: REED, S.M.; BAYLEY, W.M.; SELLON, D.C. Equine Internal Medicine, ed. Saunders, 2 ed., p.96-109, 2004. RIKIHISA, Y. Rickettsial diseases. In: REED, S.M. & BAYLY, W.M.A. (Eds). Equine Internal Medicine. Philadelphia: W.B. Saunders, p.112-123, 1998. RIKIHISA, Y.; WADA, R., REED, S.M. Development of neutralizing antibodies in horses infected with Ehrlichia risticii, Veterinary Microbiology, v.36, p.139, 1993. RIKIHISA, Y.; JOHNSON, G.J.; WANG, Y.-Z.; REED, S.M.; FERTEL, R.; COOKE, H.J. Loss of adsorptive capacity for sodium chloride as a cause of diarrhea in Potomac horse fever. Research in Veterinary Science, v.52, p. 353-362, 1992. RIKIHISA Y.; STILLS H.; ZIMMERMAN, G. Isolation and continuous culture of Neorickettsia helminthoeca in macrophage cell line. Journal of Clinical Microbiology. v.29, n.9, p.1928-1933, 1991. RIKIHISA, Y. Grown of Ehrlichia risticii in human colonic epithelial cells. In: Risckettsiology: Current issues and perspectives. New York Academy Science v.590, p.104- 110, 1990. 35 RIKIHISA, Y.; REED, S.M.; SAMS, R.A.; GORDON, J.C.; PRETZMAN, C.I. Serosurvey of horses with evidence of equine monocytic ehrlichiosis. Journal of the American Veterinary Medical Association, v.10, p. 1327-1332, 1990. RIKIHISA, Y.; JIANG, B.M. In vitro susceptibilities of Ehrlichia risticii to eight antibiotics. Antimicrobial Agents and Chemotherapy, v.32, n.7, p. 986-991, 1988. RIKIHISA, Y.; PERRY, B.D. Causative Ehrlichial organism in Potomac horse fever. Infection and Immunity, v. 49, n. 3, p. 513-517, 1985. RIKIHISA, Y.; PERRY, B.D.; CORDES, D.O. Ultraestructural study of ehrlichial organism in the large colons of ponies infected with Potomac horse fever. Infection and Immunity, v.49, p. 505-515, 1985. RIKIHISA, Y.; PERRY, B.D.; CORDES, D.O. Rickettsial link with acute equine diarrhea. Veterinary Record v.115, p.554, 1984. RISTIC, M. DAWSON, J.; HOLLAND, C.J. Susceptibility of dogs to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis (Potomac Horse Fever). American Journal of Veterinary Research, v. 49, p. 1497, 1988. RISTIC, M.; HOLLAND, C.J.; DAWSON, J.E.; SESSIONS, J.; PALMER, J. Diagnosis of equine monocytic ehrlichiosis (Potomac horse fever) by indirect immunofluorescence. Journal of American Veterinary Medical Association, v.189, p.39–46, 1986. ROBL, M.G. Potomac Horse Fever: Closing in on an unknown killer. Veterinary Clinics of North America: Equine Practice, v.80, p. 49-58, 1985. SAMPAIO, I. B. M. Estatística aplicada à experimentação animal. 2ª ed. Belo Horizonte: Editora, FEPMVZ, 2002. 265 p. SHALM, O.W.; WEISS, D.J.; WARDROP, K.J. (eds.) Veterinary Hematology, 6th ed. Blackwell Publishing. Iowa, 2010. 1206p. SCHMIDTMANN, E.T.; RICE, R.M.; ROBL, M.G.; AZAD, A.F. Search for an arthropod vector of Ehrlichia risticii. In: PROCEEDINGS OF A SYMPOSIUM ON POTOMAC HORSE FEVER. Veterinary Learning Systems Co., Lousiville, Kentucky, p.9-16 (1988) SMITH, B. P. Tratado de Medicina Interna de Grandes Animais: 1.ed. São Paulo: Manole, 1993. 900p. SPEIRS, V. C. Exame Clínico de equinos. Porto Alegre: ed. Artmed, 1°ed.1999. 366p. VAN HEECKEREN A, RIKIHISA Y, PARK J et al: Tumor necrosis factor- , interleukin-1 and prostaglandin E2 production in murine peritoneal macrophages infected with Ehrlichia risticii, Infection and Immunity, v.61, p.4333, 1993. WEISS, E.; MULDER, J.W. The Rickettsias and Chlamydias. In: N.R. Krieg and J.G. Holt (Editors), Bergey’s Manual of Systematic Bacteriology. Vol.I. Williams and Wilkins, Baltimore, p.687-739, 1984. 36 WEISS, E.; DASCH, KANG, Y-H.; WESTFALL, H.N. Substrate utilization by Ehrlichia sennetsu and Ehrlichia risticii separated from host constituents by renografin gradient centrifugation. Journal of Bacteriology, v. 170, n.11, p.5012-5017, 1988. WHITLOCK, R.H.; PALMER, J.E.; BERSON, C.E.; ACLAND, H.M.; JENNY, L.A.; RISTIC, M. Potomac horse fever: clinical characteristics and diagnostic features. In: PROCEEDINGS 27TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION VETERINARY LABORATORY DIAGNOSTICIANS, p.103-124, 1984. WILSON, J.H.; PUSTERLA, N.; BENGFORT, J.M.; ARNEY, L. Incrimination of Mayflies as a Vector of Potomac Horse Fever in an Outbreak in Minnesota. In: PROCEEDINGS 52th ANNUAL CONFERENCE EQUINE PRACTITIONERS, San Diego, CA. American Association of Equine Practitioners, v.52, p. 324-326, 1989 WOESE, C.R.; KANDLER, O.; WHEELIS, M. Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eukarya. Proc Natl Acad Sci USA, v.87, p. 4576-4579, 1990. ZIEMER, L.E.; WHITLOCK, R.H.; PALMER, J.E.; SPENCER, P.A. Clinical and hematological variables in ponies with experimental induced equine ehrlichial colitis (Potomac horse fever). American Journal Veterinary Research, v.48, p.63-67, 1987.por
dc.subject.cnpqMedicina Veterináriapor
dc.thumbnail.urlhttps://tede.ufrrj.br/retrieve/57662/2011%20-%20Erica%20Cristina%20Rocha%20Roier.pdf.jpg*
dc.originais.urihttps://tede.ufrrj.br/jspui/handle/jspui/1223
dc.originais.provenanceSubmitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-09-28T14:27:47Z No. of bitstreams: 1 2011 - Erica Cristina Rocha Roier.pdf: 982721 bytes, checksum: 24c0654d64de8a5b21a0eea5376f828c (MD5)eng
dc.originais.provenanceMade available in DSpace on 2016-09-28T14:27:47Z (GMT). No. of bitstreams: 1 2011 - Erica Cristina Rocha Roier.pdf: 982721 bytes, checksum: 24c0654d64de8a5b21a0eea5376f828c (MD5) Previous issue date: 2011-02-28eng
Appears in Collections:Doutorado em Ciências Veterinárias

Se for cadastrado no RIMA, poderá receber informações por email.
Se ainda não tem uma conta, cadastre-se aqui!

Files in This Item:
File Description SizeFormat 
2011 - Erica Cristina Rocha Roier.pdf2011 - Erica Cristina Rocha Roier959.69 kBAdobe PDFThumbnail
View/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.