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  4. Mestrado em Medicina Veterinária (Patologia e Ciências Clínicas)
Please use this identifier to cite or link to this item: https://rima.ufrrj.br/jspui/handle/20.500.14407/14206
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dc.contributor.authorSilva, Leandro Nogueira e
dc.date.accessioned2023-12-22T02:57:28Z-
dc.date.available2023-12-22T02:57:28Z-
dc.date.issued2010-08-19
dc.identifier.citationSILVA, Leandro Nogueira e. Comparação de quatro diferentes testes quantitativos de produção lacrimal em cães domésticos. 2010. 52 f. Dissertação (Mestrado em Medicina Veterinária, Patologia e Ciências Clínicas) - Universidade Federal Rural do Rio de Janeiro, Seropédica, 2010.por
dc.identifier.urihttps://rima.ufrrj.br/jspui/handle/20.500.14407/14206-
dc.description.abstractEm relação à mensuração da produção lacrimal, a técnica de leitura lacrimal com o fio de algodão embebido em uma solução indicadora de pH vem se mostrando vantajosa em relação ao Teste Lacrimal de Schirmer I (TLS I) em diversos estudos, devido à menor largura do material de teste e tempo de realização deste, o que leva a uma menor produção lacrimal reflexa e uma leitura mais próxima da produção lacrimal basal ou real. Este experimento teve como objetivos, testar diferentes tipos de fios e avaliar qual o mais indicado a realização dos testes, desenvolver um material de medição quantitativo da produção lacrimal de fio impregnado com vermelho fenol, testar outro indicador de pH, estabelecer um padrão de leitura para estes e o ZoneQuick® da Menicon e compará-los ao TLS I avaliando suas vantagens e desvantagens. Para isto, foram selecionados 50 cães da raça Beagle, machos e fêmeas, com idade variando de 1 a 8 anos do Canil do Laboratório de Quimioterapia Experimental Parasitológica da UFRRJ, e produzidos dois testes com Fio de Algodão impregnados com Vermelho Fenol ou Verde de Bromocresol. Em seguida foi feita a padronização da leitura dos três testes em comparação ao TLS I, obtendo-se como faixa normal de leitura para o Teste de Fio de Algodão com Vermelho Fenol de 13,6 a 22,7 mm/15seg., o ZoneQuick® da Menicon entre 22,7 e 37,8mm/15seg. e o Teste de Fio de Algodão com Verde de Bromocresol de 13,7 a 22,8 mm/15 seg.. Dentre os três testes, o ZoneQuick® apresentou a menor viragem na cor do indicador e o Teste de Fio de Algodão com Verde de Bromocresol a maior o que, juntamente com o menor erro padrão por este apresentado, facilita sua leitura e reduz a chance de falso positivo ou negativo. Na etapa de comparação entre os TLS I, Fio de Algodão com Verde de Bromocresol e Fio de Algodão com Vermelho Fenol este último gerou menor produção lacrimal reflexa, com uma leitura mais próxima da real.por
dc.formatapplication/pdf*
dc.languageporpor
dc.publisherUniversidade Federal Rural do Rio de Janeiropor
dc.rightsAcesso Abertopor
dc.subjectCãopor
dc.subjectSistema Lacrimalpor
dc.subjectTestes Quantitativos de Produção Lacrimalpor
dc.subjectDogeng
dc.subjectLacrimal Systemeng
dc.subjectProduction Testing Quantitative Lacrimaleng
dc.titleComparação de quatro diferentes testes quantitativos de produção lacrimal em cães domésticospor
dc.title.alternativeStandardization and comparison of three different quantitative tests of tear production in dogseng
dc.typeDissertaçãopor
dc.description.abstractOtherRegarding the measurement of tear production, the technique of reading tear with a cotton soaked in a pH indicator solution has proven to be advantageous compared to Schirmer Tears Test in many studies due to the smaller width of the test material and time for attaining this , which leads to less reflex tear production and a closer reading of basal tear production or real. This experiment aimed to develop a quantitative measurement equipment in tear production similar to the ZoneQuick® Menicon and improve it, establish a pattern of reading to those and evaluate their advantages and disadvantages. For that, we selected 50 beagle dogs, male and female, aged 1-8 years from the Canil do Laboratorio de Quimioterapia Experimental Parasitológica of UFRRJ, and produced two tests with Cotton Thread with Phenol Red and Bromocresol Green. Afterwards was made the reading standization of those three tests compared to the Schirmer tear test, getting as normal range of reading for the tests with Cotton Thread with Phenol Red 13.6 to 22.7 mm/15seg., the ZoneQuick® Menicon of between 22, 7 and 37.8 mm/15seg. and tests with Cotton Thread with the Bromocresol Green 13.7 to 22.8 mm/15seg.. Among those three tests, the ZoneQuick® showed the smallest shift in color of the indicator and the largest Cotton Thread with the Bromocresol Green which along with the smaller standard error presented by this facilitates its reading and reduces the chance of false positive or negative. In a comparison between the Schirmer Tears Test , Cotton Thread with the Bromocresol Green tests and Cotton Thread with Phenol Red latter, generated less reflex tear production, with a reading closer to the real.eng
dc.contributor.advisor1Pereira, João Telhado
dc.contributor.advisor1ID703.598.307-49por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/1757520979771094por
dc.creator.ID102.225.047-73por
dc.creator.Latteshttp://lattes.cnpq.br/2819972868576406por
dc.publisher.countryBrasilpor
dc.publisher.departmentInstituto de Veterináriapor
dc.publisher.initialsUFRRJpor
dc.publisher.programPrograma de Pós-Graduação em Medicina Veterinária (Patologia e Ciências Clínicas)por
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AND NELL B., Schirmer tear test, phenol red thread tear test, eye blink frequency and corneal sensitivity in the guinea pig, Veterinary Ophthalmology, v. 10, n. 3, p. 143-146, 2007. WESTERMEYER H. D., WARD D. A. and ABRAMS K., Breed predisposition to congenital alacrima in dogs, Blackwell Publishing Inc., Veterinary Ophthalmology, v. 12, issue 1, p. 1–5 Jan-Feb. 2009. WILLIAMS D. L., Analysis of tear uptake by the Schirmer tear test strip in the canine eye, Blackwell Publishing, Ltd., Veterinary Ophthalmology, v. 8, nº 5, p. 325–330, Sep. 2005. WILLIAMS D. L, PIERCE V., ELLOR P. M. and HEATH M. F., Reduced tear production in three canine endocrinopathies, Journal of Small Animal Practice, v. 48, issue 5, p. 252–256, May. 2007.por
dc.subject.cnpqMedicina Veterináriapor
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dc.originais.urihttps://tede.ufrrj.br/jspui/handle/jspui/2455
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